Publications by authors named "Padraig Daly"

Introduction: Penile cancer is a rare urological malignancy with an age-standardised incidence of 0.8 per 100,000 person-years [1]. Given this low incidence it has been suggested that centralised care may improve patient outcomes in relation to phallus sparing surgery and nodal assessment [2].

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  • Penile cancer (PC) is very rare in men under 45, with only a few cases reported compared to older men.
  • This study looked at men diagnosed with PC from 2016 to 2021, comparing younger men (45 and under) with older men.
  • Results showed that younger men had more spread of the cancer when diagnosed and did not survive as long compared to older patients.
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Background: Urachal remnants are a rare congenital defect resulting from failure of obliteration of a fibrous tube that connects the umbilicus to the bladder dome during embryological development. Oftentimes a urachal remnant will go undiagnosed, but occasionally a patient may present with a variety of symptoms, ultimately leading to the identification of the remnant. Given its rarity, there is very limited literature available on the management of symptomatic urachal remnants, especially in adults.

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  • Penile cancer is rare, affecting about 1 out of every 100,000 males in Europe, and one-third of these cases are linked to a virus called HPV.
  • A study at University Hospital Waterford looked at 70 men with this type of cancer from 2015 to 2020 to see how many had HPV using a test called p16.
  • The results showed that 64% of the patients tested positive for p16, and those with high-risk tumors often had HPV, suggesting that boys should get vaccinated to help prevent this cancer in the future.
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  • The study focuses on reconstructive surgery for male genital issues caused by non-cancerous diseases, assessing its psychological and functional impacts.
  • A review of 14 cases from 2018 to 2020 highlighted various conditions leading to genital abnormalities and involved diverse surgical techniques tailored to each patient's needs.
  • Findings suggest that reconstructive methods can significantly enhance both the appearance and function of the male genitalia affected by these medical issues.
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A 72 year old was referred to the Urology department with lower urinary tract symptoms (LUTS), an abnormal prostate on digital examination and a serum prostate specific antigen (PSA) level within normal limits. A flexible cystoscopy revealed no abnormality of the urethra and an obstructive prostate. Magnetic resonance imaging (MRI) revealed a 4.

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Adult Granulosa cell tumours (AGT) are a rarely reported subtype of testicular cancer with an unpredictable clinical course. We report the case of a 45 year old man who was diagnosed with a 15mm testicular adult granulosa cell tumour with no metastatic disease at presentation. A radical inguinal orchidectomy was performed with histology demonstrating no invasion of the tunica vaginalis, epididymis, spermatic cord and no lymphovascular invasion.

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Introduction: Growing interest surrounds the concept of en bloc transurethral resection of bladder tumors (ERBT). Theoretical advantages include improved adherence to oncological principles and potential yield of superior pathological specimens. Multiple ERBT methods exist.

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Objective: To describe and illustrate a novel technique of uretero-ileal anastomosis for use in urinary diversion - the Pull-through Anastomosis of Ureter To Enteric Conduit (PAUTEC). A second objective was to evaluate the surgical outcomes of the PAUTEC anastomosis.

Materials And Methods: Our novel anastomotic technique was described step-by-step and visually depicted with illustrations and the accompanying narrated video.

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Background: Microdissection testicular sperm extraction (mTESE) is the gold standard approach in sperm retrieval in men with non-obstructive azoospermia (NOA). The purpose of the study was to assess the outcomes for Irish men who have undergone mTESE with a single surgeon.

Methods: This is a retrospective, single cohort study.

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Zinner syndrome was first described in 1914 and represents the triad of unilateral renal agenesis and ipsilateral seminal vesicle cyst and ipsilateral ejaculatory duct obstruction. Seminal vesicle cysts are often asymptomatic but can also present with pain, haematospermia, or other lower urinary tract symptoms. Treatment strategies include observation and surgical excision.

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Background: Primary urethral carcinoma (PUC) is rare and accounts for < 1% of all genito-urinary cancers. There is a male predominance of 3:1 and a peak incidence in the 7th and 8th decades. The aetiology of this cancer is similar to penile cancer, and the human papilloma virus (HPV) is thought to be an essential factor in tumorigenesis.

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Objective: To assess patient-reported outcomes of oncoplastic penile reconstruction using standardized questionnaires. Whilst organ-preserving penile cancer surgery has evolved, aiming to preserve genital function, reduce psychological morbidity of radical penectomy, and maximise patient quality of life, few studies have evaluated patients' final perceptions.

Methods: Following ethical approval, patients post partial/radical glansectomy with reconstruction 2016-2019, under a single surgeon, were identified.

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  • Paratesticular soft tissue tumours are very rare, and about 30% of them can be cancerous.
  • In a hospital that serves around 400,000 people, they saw three cases in just over a year, all in older men with swelling on one side of their testicles.
  • After surgery to remove the tumours, doctors found different types of high-grade cancers, emphasizing the need for special medical teams to handle these tricky cases properly.
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  • The study looked at injuries to the groin area caused by playing hurling over ten years.
  • Out of 70 patients with these injuries, 10 (14%) were due to hurling, mostly affecting young men around 24 years old.
  • The research suggests that players should wear protection to prevent these injuries, especially those who are more likely to get hurt.
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Introduction: To assess the benefits and complications of developing a practice of single-stage primary ureteral stenting in a university hospital.

Methods: A practice change developed from the traditional practice of multi-stage stenting to single-episode stent placement. To evaluate this change of practice, we retrospectively analysed data of 70 patients who underwent primary tubeless antegrade ureteric stenting and compared this group to the previous 54 patients who had a covering nephrostomy.

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Epididymo-orchitis is a common urological condition in men of all ages, causing a unilateral or bilateral swelling of the epididymis and/or testis. It is frequently caused by sexually transmitted infections, Chlamydia trachomatis and Neisseria gonorrheae, as well as common enteric organisms implicated in urinary tract infections. Men over 35 years old may develop epididymo-orchitis associated with enteric organisms, often associated with functional bladder outlet problems such as benign prostatic hyperplasia or urethral stricture disease.

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Urinary tract infections are one of the most common infectious diseases diagnosed in the community and in the hospital setting. Their treatment is complicated by drug-resistant pathogens and the colonization by microbes of indwelling urinary catheters. This study assessed the occurrence and antimicrobial susceptibility of methicillin-resistant Staphylococcus aureus (MRSA) uropathogens isolated for 5 consecutive years at University Hospital Waterford between 2010 and 2014.

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  • Penile cancer is rare but can really affect a person's body, feelings, and life.
  • Instead of removing the whole penis (total penectomy), doctors now have better ways to treat it that keep more of the penis and help with body image and sexual function.
  • Choosing the right treatment depends on how much the cancer has spread, and while there is a risk of the cancer coming back, patients can do well if they follow strict check-ups and understand the risks.
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Background: We assess our long-term experience with regards the safety and efficacy of Mycophenolate Mofetil (MMF) in our low risk renal transplant population and compared it retrospectively to Azathioprine (AZA) immunosuppressive regimen. Patients and methods. Between January 1999 and December 2005, 240 renal transplants received MMF as part of their immunosuppressive protocol (MMF group).

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Rhabdomyosarcoma (RMS), arising from mesenchymal cells, is the most common soft tissue tumour in children and accounts for up to half of all sarcomas. We present the case of a 33-year-old male presented to the urology department of the University College Hospital Galway (Ireland) in March 2009 with a 2-month history of a left scrotal swelling, increasing in size.

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Purpose: We examined the process and causes of diagnostic delay, defined as the interval from symptom onset to diagnosis, for testis (germ cell) cancer and the change with time. Diagnostic delay influences disease burden and may be subdivided into symptomatic interval, defined as symptom onset to first presentation, and diagnostic interval, defined as first presentation to diagnosis.

Materials And Methods: We performed a single center review of 100 consecutive cases.

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  • A study was done on male and female rats to see how their kidneys reacted after a blockage in their ureters (tubes that carry urine from the kidneys).
  • The researchers found that male rats had more kidney damage compared to female rats after the blockage was fixed, but both genders had similar abilities to concentrate their urine.
  • They concluded that even after the blockage was removed, male rats showed more signs of kidney injury, which could be due to changes in certain kidney functions and proteins.
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Introduction: The aim of this study was to determine the cardiovascular (CV) risk factor response in Irish patients with type 1 diabetes following simultaneous pancreas and kidney transplantation (SPK), analyzing response based on mode of immunosuppression and surgical drainage in a uniquely homogenous population.

Methods: A retrospective review of SPKs carried out between 1993 and 2005 in the National Renal and Pancreatic Centre of Ireland was performed. Weight, glycated hemoglobin (HBA1c), lipid profile, and blood pressure (BP) were measured pre- and post-operatively.

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Objectives: To assess for predictors of outcome in patients presenting with acute urinary retention (AUR).

Methods: A study was performed in our unit to evaluate trial without catheter (TWOC) and successive management. We assessed for predictors of surgical or medical management, which included: age, volume drained at time of catheterisation, cause of retention, serum creatinine, success of trial of voiding, co-morbidities, prostate-specific antigen (PSA) and prostate size on digital rectal examination (DRE).

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