Exploring Nose to Brain Nano Delivery for Effective Management of Migraine.

Migraine is a disabling disease characterized by severe throbbing headaches. Patients demand quick relief from this pain. The presence of the blood-brain barrier does not permit the drug to penetrate the brain effectively.

Emerging topical drug delivery approaches for the treatment of Atopic dermatitis.

Background: Atopic dermatitis is a chronic, relapsing skin inflammation disease that generally affects 20% of children and 1-3% of adults. It is characterized by pruritus, inflammatory skin lesions, and skin barrier defect. The pillar treatment is topical therapies that have shown great adherence and incredible results in alleviating symptoms of atopic dermatitis.

Alternative Wound Management: Translating Science into Practice.

General Purpose: To present a scoping review of preclinical and clinical trial evidence supporting the efficacy and/or safety of major alternative wound care agents to summarize their effects on validated elements of wound bed preparation and wound management paradigms.

Target Audience: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care.

Learning Objectives/outcomes: After participating in this educational activity, the participant will:1.

Novel user-friendly night care spray to manage skin darkening.

Background: Hyperpigmentation can be either diffused or localized. In treating diffused hyperpigmentation, larger surface area coverage is the requirement. Novel user-friendly spray formulation loaded with depigmenting agents can cater the night time need in treating skin darkening.

Advances in encapsulated dermal formulations in chemoprevention of melanoma: An overview.

Background: The three forms of skin cancer are cutaneous malignant melanoma, basal cell carcinoma, and squamous cell carcinoma. Melanoma skin cancer is an aggressive type and one of the most chemotherapy-resistant malignancies. Conventional topical products are beset with limitations, leading to lower efficacy.

Skin delivery of resveratrol encapsulated lipidic formulation for melanoma chemoprevention.

An unmet need for patient friendly products can be achieved with novel, biocompatible lipidic formulations which encapsulate and prolong release of medicaments. The aim of this study was to develop a commercially scalable resveratrol-loaded solid-lipid microparticulate (SLM) topical gel for melanoma chemoprevention. Preformulation studies were conducted and drug-excipient interactions examined using infra-red spectroscopy and differential scanning calorimetry (DSC).

An overview of herbal alternatives in androgenetic alopecia.

The second most common alopecia-Androgenetic alopecia (AGA)-occurs due to hormonal imbalance. Dihydrotestosterone (DHT) an androgenic hormone is a sex steroid, produced in the gonads. The target sites of DHT are similar to that of testosterone, and it attaches easily remaining bound for 53 minutes as compared to 35 minutes of testosterone.