Publications by authors named "Padma Madakasira Vasantha"
Article Synopsis
- A study was conducted to see if a mobile app could help neurology trainees improve their ability to identify differential diagnoses in Neuro-ophthalmology.
- The research involved comparing the accuracy of 100 neurology residents against the app (Neurology Dx) using 1500 clinical scenarios, with the app performing significantly better (53.71% vs. 19.42%) in identifying correct diagnoses.
- The findings suggest that using the mobile app can enhance clinical reasoning and diagnostic accuracy for neurology residents.
Background And Purpose: This study was performed to elucidate quality of life (QOL) and its determinants in adult drug refractory epilepsy (DRE) patients who were not candidates for epilepsy surgery.
Methods: A correlational study was performed at the center of excellence, epilepsy between July 2014 to June 2016. All consecutive DRE patients who were not candidates for epilepsy surgery were enrolled.
Background And Purpose: To identify predictors of seizure-related injury (SRI) and death in people with epilepsy (PWE) in a North Indian cohort.
Methods: This ambispective cohort study included PWE registered in an epilepsy clinic in Delhi between May 2010 and December 2011. Five hundred twenty-six patients were enrolled and followed for 25 months.
Objectives: An accurate description of the seizure semiology improves the recognition of the ictal onset zone and helps in hypothesizing the possible epileptogenic zone (EZ). Semiology based on a reliable description of seizures may be as good as investigative modalities, as has been shown by numerous studies. The main objective of this study was to apply a questionnaire-tool for auras and semiology (QUARAS) in refractory epilepsy cohort and compare its yield to that of standard history-taking.
View Article and Find Full Text PDFObjectives: The study aimed to evaluate the feasibility and yield of semiological features from home videos and compare them to those inferred from history provided by the caregiver of a person with epilepsy (PWE). A comparison of the accuracy of classification of epilepsy based on home videos and medical history was also done.
Methods: We enrolled PWEs who were awaiting admission for video electroencephalography (VEEG) to the epilepsy monitoring unit (EMU) in this prospective observational study.
Objective: The loss of function mutations (biallelic) in frataxin (FXN) has primarily been implicated in Friedreich's ataxia (FRDA), an autosomal recessive cerebellar ataxia. The protein product of FXN is a nuclear-encoded mitochondrial protein required for the biogenesis of iron- clusters (Fe-S). FRDA is characterized by neurological and non-neurological features which show variable expression in affected individuals.
View Article and Find Full Text PDFPurpose: The present study was conducted with the aim of evaluating the effects of reducing the number of antiepileptic drugs (AEDs) administered to patients with drug-refractory epilepsy (DRE) during their admission and document any change in seizure frequency in subsequent follow up.
Methods: A total of 962 patients with DRE who were admitted to the neurology wards waiting for connection to video EEG were recruited for this prospective study. After their admission to the neurology ward, modifications in the number and dosage of AEDs were done with a target of a maximum of three AEDs in every patient.
Background And Purpose: Stroke in young adults has a special significance in developing countries, as it affects the most economically productive group of the society. We identified the risk factors and etiologies of young patients who suffered ischemic strokes and were admitted to a tertiary referral hospital in North India.
Methods: A retrospective review of case records from patients with ischemic stroke in the age range of 18-45 years was conducted from 2005 to 2010.
Objectives: To review clinical characteristics and response to immunomodulation therapy in autoimmune encephalitis presenting with status epilepticus (SE), epilepsy, and cognitive decline.
Design: Observational, prospective case series.
Setting: All India Institute of Medical Sciences, New Delhi, India.
Background: Little is known about the impact of premorbid undernutrition on stroke outcome in developing countries.
Aim: To study the impact of premorbid undernutrition status, measured by the Subjective Global Assessment (SGA) tool, on short term stroke outcome.
Methods: First ever stroke patients admitted to six major hospitals in North and South India participated in this study from 1 March 2008 to 30 September 2009.