Publications by authors named "Pacome Kouadio N'Go"
Transl Neurosci
January 2021
Article Synopsis
- Alzheimer's disease (AD) is increasingly threatening African populations due to longer life expectancies, prompting research into natural products like catechin and dimeric procyanidins for potential cognitive protection.
- adult male Wistar rats were used in experiments where Aβ was injected to mimic AD, followed by treatments with melatonin or the extract to assess cognitive abilities and oxidative stress levels.
- Results showed that the extract reduced cognitive impairments and oxidative stress induced by Aβ, suggesting its potential neuroprotective effects are comparable to melatonin, but further pharmacological studies are needed to validate these findings.
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