Publications by authors named "Paco Real"
Article Synopsis
- The study focuses on analyzing CD8+ cytotoxic lymphocytes in bladder cancer, particularly in non-muscle invasive bladder cancer (NMIBC), to understand their role in the immune response against tumors.
- A standardized method was developed for estimating CD8+ cell counts using tissue samples from a large cohort, revealing significant spatial heterogeneity in immune cell infiltration between different tumor stages.
- The findings indicate that CD8+ infiltration varies with tumor stage but does not correlate with patient prognosis, highlighting the need for careful study design in future research.
Embryonic stem (ES) cells which constitutively express the Pdx-1, Ngn-3, NeuroD1, Nkx2.2, and Nkx6.1 transcription factors were engineered by means of lentiviral vectors, following a multi-step infection procedure to successively generate ES cell lines expressing one, two, and three factors, respectively.
View Article and Find Full Text PDF