Publications by authors named "Packiyam Thamarai"

The emergence of checkpoint inhibitors targeting the PD-1/PD-L1 axis marks a paradigm shift in cancer therapy, offering a novel avenue for enhancing patient outcomes. This review examines the structural and functional dynamics of PD-1 and PD-L1 while exploring the clinical implications of current PD-1/PD-L1 monoclonal antibodies. Highlighting recent advancements, this paper delves into the promising results from combination therapies that present a multifaceted attack on tumor progression.

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Article Synopsis
  • Stem cell therapy shows great potential for treating various diseases and injuries, but its widespread use is hindered by challenges like ineffective differentiation and low survival rates post-transplantation.
  • * Recent advancements in nanotechnology, including nanoparticles and quantum dots, have been found to enhance stem cell differentiation and proliferation by creating optimal microenvironments and delivering growth factors effectively.
  • * The integration of nanotechnology into stem cell therapy paves the way for precision medicine, allowing for better control of stem cell behavior and the potential for personalized and effective treatments.
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The persistence of organic/inorganic pollutants in the water has become a serious environmental issue. Among the different pollutants, dyes and heavy metal pollution in waterways are viewed as a global ecological problem that can have an impact on humans, plants, and animals. The necessity to develop a sustainable and environmentally acceptable approach to remove these toxic contaminants from the ecosystem has been raised.

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