Publications by authors named "Pacheco-Barrios N"

Introduction: Low back pain is common during pregnancy, affecting up to 76% of women. However, symptomatic lumbar disc herniation (LDH) is rare, occurring in about 1 in 10,000 pregnancies, with less than 2% progressing to cauda equina syndrome (CES). The overlap in symptoms between LDH and typical pregnancy-related conditions complicates both diagnosis and management.

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Background: Deep brain stimulation (DBS) is a standard treatment for movement disorders, epilepsy, and others, yet its influence on postprocedural sleep quality remains an under-researched topic.

Study Objectives: We performed a systematic review and meta-analysis of all DBS effects on sleep.

Methods: The use of preferred reporting items for systematic reviews and meta-analyses guidelines (PRISMA) was utilized.

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Background: Perioperative bleeding is a challenge in rhinoplasty and septoplasty. Tranexamic acid (TXA) may help reduce this, but its effectiveness is unclear. This systematic review and meta-analysis aimed to evaluate TXA's impact on bleeding in these procedures.

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In the management of traumatic brain injury (TBI), intracranial pressure monitoring (ICPm) is crucial for the timely management of severe cases that show rapid neurological deterioration. External ventricular drains (EVDs) and intraparenchymal pressure monitors (IPMs) are the primary methods used in this setting; however, the debate over their comparative efficacy persists, primarily because of reliance on observational study data. This underscores the need for a meta-analysis to guide clinical decision-making.

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Article Synopsis
  • Chronic subdural hemorrhage (cSDH) is a common neurosurgical condition, and this systematic review aimed to identify risk factors for seizures following its treatment.* -
  • The review analyzed 18 studies with nearly 5000 patients, finding a 10% overall seizure incidence after treatment, with lower risks associated with burr hole surgery compared to craniotomy.* -
  • The findings suggest a need for standardized reporting and more comparative research to better understand seizure risks post-cSDH treatment, particularly regarding the effectiveness of prophylactic antiepileptic medications.*
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  • Harlequin syndrome (HS) is a rare condition that results in uneven flushing and sweating, often due to issues with the sympathetic nervous system. When it's linked to external damage, it's called Harlequin Sign.
  • *In a systematic review of the literature, researchers analyzed 1,538 studies, finding 8 case reports of Harlequin Sign associated with upper thoracic paravertebral lesions, primarily in middle-aged females.
  • *The study identified that symptoms like hemifacial flushing and anhidrosis were common, and while CT scans were mainly used for diagnosis, surgical intervention was only successful in resolving symptoms for a quarter of the patients.
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Background: High-grade gliomas (HGG) are the most aggressive primary brain tumors with poor prognoses despite conventional treatments. Immunotherapy has emerged as a promising avenue due to its potential to elicit a targeted immune response against tumor cells.

Objective: This meta-analysis aimed to evaluate the efficacy and safety of various immunotherapeutic strategies, including immune checkpoint inhibitors (ICI), virotherapy, and dendritic cell vaccines (DCV) in treating HGG.

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Introduction: The burden of multimorbidity is recognised increasingly in low- and middle-income countries (LMICs), creating a strong emphasis on the need for effective evidence-based interventions. Core outcome sets (COS) appropriate for the study of multimorbidity in LMICs do not presently exist. These are required to standardise reporting and contribute to a consistent and cohesive evidence-base to inform policy and practice.

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Objective: Anterior choroidal artery (AChA) aneurysms account for 2%-5% of all intracranial aneurysms. Treatment considerations include microsurgical clipping, flow diversion, or coiling with or without adjunctive devices. AChA aneurysms pose challenges in treatment due to the origination of the aneurysm from the origin or proximal segment of the AChA.

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Background: Gluteoplasty or gluteal augmentation is a popular cosmetic procedure that is used to improve the volume, shape, and contour of the buttocks.

Objectives: This bibliometric analysis aims to characterize emerging research trends and to assess the methodological quality of the highest impact gluteoplasty research.

Methods: The 100 most-cited publications in gluteoplasty were identified on Web of Science, across all available journal years (from Inception to August 2023).

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Background: Endovascular options for the treatment of basilar apex aneurysms (BAAs) are heterogeneous, and evidence is limited to retrospective cohorts and case series. We seek to evaluate the efficacy and complications associated with various endovascular treatment methods of BAAs.

Methods: Systematic review of PubMed, Embase, and Web of Science adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

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The demand for palliative care is increasing globally, yet a notable lack of awareness continues to present a significant obstacle to its widespread adoption. The use of digital tools like Google Trends can help gauging public interest in specific topics. We used Google Trends to conduct a systematic search of terms related to palliative care from January 1, 2010, to May 10, 2023.

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Background And Objectives: Postoperative seizures are a common complication after surgical drainage of nonacute chronic subdural hematomas (SDHs). The literature increasingly supports the use of prophylactic antiepileptic drugs for craniotomy, a procedure that is often associated with larger collections and worse clinical status at admission. This study aimed to compare the incidence of postoperative seizures in patients treated with burr-hole drainage and those treated with craniotomy through propensity score matching (PSM).

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Article Synopsis
  • * The research compared brain lesions causing parkinsonism with those causing seizures using advanced brain network mapping techniques.
  • * Findings indicate that lesions related to parkinsonism and seizures are associated with distinct, opposite brain networks, particularly highlighting the role of the substantia nigra in this relationship.
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Awake craniotomy has emerged as an advanced surgical technique, characterized by keeping the patient awake during brain surgery. In South America, awake craniotomies have grained traction in neurosurgical practices across various medical centres and hospitals, with notable practitioners contributing to its growth and refinement in the region. This study aims to explore the integration and impact of awake craniotomies in South American neurosurgical practices.

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Exploring the landscape of intracranial aneurysms in South America unravels a complex interplay of epidemiological factors, clinical manifestations, and therapeutic challenges. The study methodically conducts a comprehensive literature review spanning the years 2003 to 2023, focusing on English-language articles obtained from diverse databases to elucidate the multifaceted nature of intracranial aneurysms in the region. Results and discussions categorize outcomes into positive domains, emphasizing successful treatments, favorable recoveries, and high survival rates, while also shedding light on negative aspects such as residual aneurysms and complications.

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