AN INVESTIGATION OF AN AMYLOID-LIKE DEPOSITION DISORDER IN REPTILES.

Amyloidosis is the pathologic extracellular deposition of amyloid, a proteinaceous substance, in various tissues and organs. The most common form of amyloidosis in domestic animals is amyloid A amyloidosis, though amyloid light chain, amyloid β, and islet amyloid polypeptide amyloidosis have been documented. In reptiles, amyloidosis, or amyloid-like disorders, are considered rare.

Ant assemblages (Hymenoptera: Formicidae) and spatial patterns of diversity along Cerrado remnants in Central-West Brazil.

Ants are a diverse and ecologically important group of social insects, playing a key role in ecosystem functioning. However, significant gaps remain in our understanding of their distribution across the Brazilian biomes. In this study, we surveyed four sites within a poorly sampled region of the Cerrado, located between Mato Grosso (MT) and Goiás (GO) states in Brazil.

Inhibition of Fusarium oxysporum growth in banana by silver nanoparticles: In vitro and in vivo assays.

Fusarium wilt is a devastating disease that affects banana crops worldwide. In Ecuador, bananas are one of the most important commodities and staple food. Nanoparticles are emerging as innovative solutions to control fungal diseases in plant protection.

Primary adenocarcinoma of the urinary tract and its precursors: Diagnostic criteria and classification.

Primary adenocarcinoma of the urinary bladder is a rare malignancy, comprising up to 2% of bladder cancers, predominantly in males. Its rarity and similarity to urothelial carcinoma and secondary adenocarcinomas pose diagnostic challenges. A comprehensive literature review was conducted on the diagnosis, classification, morphological and immunophenotypic characteristics, and molecular profiles of primary adenocarcinoma, urachal adenocarcinoma, and precursor lesions.

Giant cell tumour of the larynx-a diagnostic challenge.

Giant cell tumours (GCTs) of the larynx are extremely rare. The most affected structure is the thyroid cartilage and only 44 cases are reported in the literature. Clinically, their first manifestation is usually a palpable neck mass, often accompanied by hoarseness, dyspnoea, and/or dysphagia depending on size and location.

Incidence and Pitfalls of Intratesticular Adipose Tissue Encountered in Orchiectomy Specimens.

Based on the eighth edition of the American Joint Committee on Cancer staging system, postpubertal germ cell tumors (GCT) and malignant sex cord-stromal tumors (SCST) of the testis invading hilar soft tissue are of pathologic stage pT2. Adipose tissue is typically used as an anatomical landmark by pathologists for determining hilar soft tissue invasion. Herein, we evaluated for the presence, location, and extent of intratesticular fat in a multi-institutional cohort of orchiectomies.

Diagnosis of Mycobacterium leprae in free-living animals in a hyperendemic area in Brazil.

Mycobacterium leprae (M. leprae) is a globally distributed intracellular pathogen that causes human leprosy. For many years, M.

Gamna-Gandy bodies in renal neoplasms: A multi-institutional clinicopathologic study of 350 consecutive nephrectomies.

Gamna-Gandy (GG) bodies are sclerosiderotic nodules composed of iron pigment and calcium, that have been described predominantly in the spleens of patients with sickle cell disease. Their formal depiction in the kidney is mainly limited to case reports and small series. We aimed to investigate the incidence of GG bodies and associated clinicopathologic features in consecutive nephrectomies performed for renal tumors.

Delphi technique for design and content validation by experts of a mobile app for self-care of breast cancer-related lymphedema.

Introduction: Breast cancer-related lymphedema (BCRL) is a complication that requires lifelong control, with patients taking responsibility for self-care. Mobile applications (apps) can be an effective health education strategy to help manage BCRL by promoting collaborative learning environments in physical therapy. The objective of this study was to design and validate the content for the development of a mobile application for self-care in the health of the BCRL.

Conclusions of clinical trials assessing monoclonal antibodies and sponsored by pharmaceutical industry: a meta-research study.

Objective: The objective of this study was to describe and critically appraise the conclusions of randomized clinical trials assessing monoclonal antibodies sponsored by the pharmaceutical industry.

Methods: This is a meta-research study on conclusions' characteristics of randomized clinical trials with monoclonal antibodies as interventions sponsored by the pharmaceutical industry.

Results: A total of 82 publications were considered.

Valorizing sardine scales: a circular approach to sustainable collagen for cosmetics and nutrition applications.

Background And Objective: In recent years, the consumption of fish products has led to a worrying trend where approximately two-thirds of the total amount of fish is discarded as waste. At the same time, scientific interest in exploring natural collagen sources for cosmetics and dietary supplements has increased. This study explores the potential of valorizing sardine scales (), a by-product of the canning industry, through the extraction of collagen for potential use in dermocosmetic formulations and food supplements.

Restoration of Non-carious Cervical Lesions: A Brief Review for Clinicians.

Non-carious cervical lesions (NCCLs) become common in individuals over the age of 40 and are progressive. Those that are wedge-shaped in cross-section likely develop hazardous stress concentrations along their sharp axial extent, which can be distributed to lower, safer levels over a larger area via adhesive restoration. Restoration is indicated once a lesion progresses to a minimum restorable axial depth of at least 1.

Impact of Battery Levels of a Cordless LED Curing Unit on Resin Cement under Varied Lithium Disilicate Thicknesses and Translucencies.

Objectives: This study aimed to evaluate the impact of battery levels on the emission of a multi-peak cordless LED light-curing unit (LCU) and the effect on the degree of conversion (DC) and Knoop hardness (KH) of a light-cure resin luting agent activated through varying lithium disilicate (LiS2) ceramic thicknesses and translucencies.

Methods: High and low translucency LiS2 discs (IPS e.max Press HT and LT, respectively; shade A1) with thickness of 0.

Advanced therapy with mesenchymal stromal cells for knee osteoarthritis: Systematic review and meta-analysis of randomized controlled trials.

Background: Advanced cell therapies emerged as promising candidates for treatment of knee articular diseases, but robust evidence regarding their clinical applicability is still lacking.

Objective: To assess the efficacy and safety of advanced mesenchymal stromal cells (MSC) therapy for knee osteoarthritis (OA) and chondral lesions.

Methods: Systematic review of randomized controlled trials conducted in accordance with Cochrane Handbook and reported following PRISMA checklist.

Chemokinergic and Dopaminergic Signalling Collaborates through the Heteromer Formed by CCR9 and Dopamine Receptor D5 Increasing the Migratory Speed of Effector CD4 T-Cells to Infiltrate the Colonic Mucosa.

Inflammatory bowel diseases (IBDs) involve chronic inflammation of the gastrointestinal tract, where effector CD4 T-cells play a central role. Thereby, the recruitment of T-cells into the colonic mucosa represents a key process in IBD. We recently found that CCR9 and DRD5 might form a heteromeric complex on the T-cell surface.

Methodological and reporting quality of systematic reviews on aesthetics and reconstructive breast surgery: A meta-research.

Objective: To evaluate the methodological and reporting quality of systematic reviews (SR) of randomized controlled trials on esthetics and reconstructive breast surgery.

Methods: Meta-research study with a broad search strategy was developed to retrieve all relevant systematic reviews. We evaluated the methodological and reporting guidance adopted by these reviews and assessed their adequacy to items from AMSTAR-2 (methodological quality) and PRISMA 2020 (reporting quality).

A novel simplified method for assessing crystal length and crystalline content in dental ceramics.

The purpose of this study was to introduce a novel and simple method of evaluating the crystal length and crystalline content of lithium disilicate dental ceramics using images obtained from scanning electron microscopy (SEM) and analyzed with ImageJ (NIH) processing software. Three evaluators with varying experience levels assessed the average crystal length and percentage of crystalline content in four commercial lithium disilicate reinforced glass ceramic materials: IPS e.max (Ivoclar Vivadent), Rosetta SM (Hass), T-Lithium (Talmax), and IRIS CAD (Tianjin).

Treatment for multidrug-resistant tuberculosis: A comparative analysis of programmatic outcome indicators between Buenaventura and other municipalities of Valle del Cauca, Colombia.

Introduction. Proper management of multidrug-resistant tuberculosis is a prioritized strategy for tuberculosis control worldwide. Objective.