Outcomes and Trends of Open Thoracotomy and Video-Assisted Thoracic Surgery for Surgical Management of Catamenial Pneumothorax: A 10-Year Retrospective Cohort Study of a Thai Population.

Background Catamenial pneumothorax (CP) is characterized by pneumothorax associated with menstrual cycles and thoracic endometriosis. This study aimed to review the outcomes and trends for surgical treatment of CP in King Chulalongkorn Memorial Hospital. Methodology We included females aged 18 to 50 years who underwent surgery for CP between January 2012 and December 2022.

Cannabidiol/cannabidiolic acid-rich hemp (Cannabis sativa L.) extract attenuates cognitive impairments and glial activations in rats exposed to chronic stress.

Ethnopharmacological Relevance: Hemp (Cannabis sativa L.) is increasingly being recognized for its medicinal properties beside utilizing it for food, oil, and textile fibers. The high level of cannabidiol (CBD) content in hemp's flowers shows promising neuroprotective properties without causing psychotomimetic or addictive effects.

Expanding the roles of malaria post workers in Thailand: A qualitative study of stakeholder perspectives.

In Thailand, since the 2000s, malaria post (MP) workers have been tasked with promptly detecting and treating all malaria cases to prevent onward transmission in the communities. Expanding their roles to provide health services beyond malaria has been proposed as a strategy to sustain their activities until elimination is reached. This article examines the perspectives of stakeholders on community-based malaria care to assess prospects for expanding the role of MPs.

Mathurameha ameliorates cardiovascular complications in high-fat diet/low-dose streptozotocin-induced type 2 diabetic rats: insights from histological and proteomic analysis.

Type 2 diabetes mellitus (T2DM) is a global health concern with increasing prevalence. Mathurameha, a Thai herbal formula, has shown promising glucose-lowering effects and positive impacts on biochemical profiles in diabetic rats. The present study investigated the protective effects of Mathurameha on cardiovascular complications in high-fat diet/streptozotocin (HFD/STZ)-induced type 2 diabetic rats using histological and proteomic analyses.

The Safety Assessment of Mutagenicity, Acute and Chronic Toxicity of the (Kurz) Hook.f. Water Leaf Extract.

(Kurz) Hook.f. has traditionally been used as an anti-insecticidal agent and as a medication due to its hepatoprotective properties by highland communities in Thailand.

SWATH-proteomics reveals Mathurameha, a traditional anti-diabetic herbal formula, attenuates high glucose-induced endothelial dysfunction through the EGF/NO/IL-1β regulatory axis.

Mathurameha is a traditional Thai herbal formula with a clinically proven effect of blood sugar reduction in patients with diabetes mellitus, but its anti-diabetic complication potential is largely unknown. This study aimed to elucidate the effects of Mathurameha and its underlying mechanisms against high glucose-induced endothelial dysfunction in human endothelial EA.hy926 cells.

Tetrahydroxanthene-1,3(2)-diones and Oxidized Hexadiene Derivatives from and Their Biological Activities.

The first phytochemical investigation of the twig extract of resulted in the isolation and identification of three new tetrahydroxanthene-1,3(2)-diones, uvarialeptones A-C, two new oxidized hexadiene derivatives, uvarialeptols A and B, together with ten known compounds. Their structures were elucidated by spectroscopic techniques and mass spectrometry. Uvarialeptones A and B were unprecedented tetrahydroxanthene-1,3(2)-dione dimers which exhibited a cyclobutane ring via [2 + 2] cycloaddition from uvarialeptone C and 9a--methyloxymitrone, respectively.

Effects of cassava wax bath as a new therapeutic approach on patients with plantar fasciitis: a double-blind, randomised clinical trial.

The aim of this study was to investigate the efficacy of a new therapeutic approach (cassava wax bath: CWB) compared with usual care (paraffin wax bath: PWB) in patients with plantar fasciitis (PF). Forty patients with PF were recruited into the study (CWB group, n = 20, PWB group, n = 20). Patients in the CWB group received cassava wax bath and patients in the PWB group received usual care (PWB).

Highly oxygenated cyclohexenes from Uvaria dac Pierre ex Finet & Gagnep. and their α-glucosidase inhibitory activity.

Phytochemical investigations of the twig and leaf extracts of Uvaria dac Pierre ex Finet & Gagnep. resulted in the isolation and identification of five new highly oxygenated cyclohexenes, uvaridacols M - Q (1-3, 5, and 6), and six known compounds (4 and 7-11). All new structures were elucidated by spectroscopic methods and HRESITOFMS data.

Aporphine alkaloids and a naphthoquinone derivative from the leaves of Phaeanthus lucidus Oliv. and their α-glucosidase inhibitory activity.

Three previously undescribed aporphine alkaloids, phaeanthuslucidines E-G, one previously undescribed naphthoquinone derivative, phaeanthusnaphthoquinone, and three known compounds were isolated from an EtOAc extract of the leaves of Phaeanthus lucidus Oliv. The structures of all previously undescribed compounds were established through extensive spectroscopic investigations and high-resolution mass spectroscopy. The 6aR configuration of phaeanthuslucidines E-G was assigned by comparing their ECD spectra and specific rotation values with the reported known compounds.

Styryl lactone derivatives and aristolactam alkaloids from Miq. and their α-glucosidase inhibitory activity.

Two new styryl lactone derivatives, goniothapic acids A () and B (), and 18 known compounds, were isolated from the twig and leaf extracts of Miq. The structures of new compounds were characterised by spectroscopic methods and HRESITOFMS. Their absolute configuration was established by comparing the experimental and calculated ECD spectra.

Promising Anti-Wrinkle Applications of Aromatic Extracts of J. Koenig via Antioxidation and Collagenase Inhibition.

This study aimed to extract aromatic compounds from the rhizomes, leaf sheaths, and leaves of and investigate their chemical compositions, cosmetic/cosmeceutical activities, and irritation potency. The chemical compositions were investigated via gas chromatography-mass spectrometry. The antioxidant activities were evaluated via spectrophotometry.

Anti-inflammatory potential of a Thai traditional remedy called Prabchompoothaweep in an animal model of acute and sub-acute inflammation.

Ethnopharmacological Relevance: Prabchompoothaweep (PCT) is a Thai remedy which is composed of 23 herbs and has been added onto the National List of Essential Medicines (NLEM) of Thailand. This remedy has been used to treat allergic rhinitis and asthma in Thai traditional medicine for many years. Furthermore, a few studies have reported anti-allergic, anti-malarial, anti-inflammatory and antioxidant activities.

Study of Optimal Conditions to Grow Thai , Fruiting Test, Proximate and Their Alpha Glucosidase Inhibitory Activity.

() has a worldwide distribution and has been widely used in traditional medicines. In this study, we report wild strains of that include two and one from northern Thailand. Optimal conditions for mycelium growth were ensured.

Phaeanthuslucidines A-D, dimeric aporphine alkaloid derivatives from Phaeanthus lucidus Oliv.

The first phytochemical investigation of the twigs of Phaeanthus lucidus Oliv. resulted in the isolation and identification of four undescribed alkaloids, including two aporphine dimers, phaeanthuslucidines A and B, a hybrid of aristolactam-aporphine, phaeanthuslucidine C, and a C-N linked aporphine dimer, phaeanthuslucidine D, together with two known compounds. Their structures were determined by extensive analysis of spectroscopic data, and by comparison of their spectroscopic and physical data with previous reports.

Alkaloids and Styryl lactones from King and Their -Glucosidase Inhibitory Activity.

Gonioridleylactam (), a new compound, is a unique dimeric aristolactam isolated from the EtOAc extract of the twigs of King. The structure of gonioridleylactam () consists of two different aristolactams linked together with two methylenedioxy bridges at C-3/C-3' and C-4/C-4', generating a ten-membered ring of [1,3,6,8]tetraoxecine. A new natural product, gonioridleyindole (3-hydroxymethyl-1-methyl-1-benz[]indole-4,9-dione, ), together with eight known compounds () were also isolated from this plant.

Dimeric aporphine alkaloids from the twigs of Trivalvaria costata (Hook.f. & Thomson) I.M.Turner.

A phytochemical investigation of the twig extract of Trivalvaria costata (Hook.f. & Thomson) I.

Rotenoids and isoflavones from the leaf and pod extracts of Millettia brandisiana Kurz.

Phytochemical investigations of the leaf and pod extracts of Millettia brandisiana Kurz led to the isolation and identification of four previously undescribed rotenoids, (-)-(6aS,12aS)-millettiabrandisins A-C and (-)-(6aS,12aS)-6-deoxyclitoriacetal, two previously undescribed isoflavones, millettiabrandisins D and E, and 20 known compounds. The structures of previously undescribed compounds were determined on the basis of NMR and MS data. The absolute configurations of (-)-(6aS,12aS)-millettiabrandisins A-C were determined from the comparison of their experimental and calculated ECD spectra.

Rhizome Extract as Potential Anti-Acne Ingredient.

(Black ginger) is used widely in medical fields as an anti-microorganism and anti-inflammation. In this study, the aim was to evaluate the in vitro and in vivo anti-acne efficacy of black ginger extract. The results indicate that the methanol and ethanol extracts showed the highest total phenolic contents, without a significant difference, whereas the -hexane extract showed the highest total flavonoid content.

Antidiabetic and Cytotoxic Activities of Rotenoids and Isoflavonoids Isolated from Benth.

A phytochemical investigation of the root and leaf extracts of Benth resulted in the isolation and identification of 16 compounds, including six rotenoids (-) and 10 prenylated isoflavonoids (-). Compound was isolated as a scalemic mixture, which was resolved by chiral HPLC to afford (-)-(6a,12a)-12a-hydroxy-α-toxicarol () and (+)-(6a,12a)-12a-hydroxy-α-toxicarol (). (+)-(6a,12a)-Millettiapachycarpin () and (-)-(6a,12a)-12a-hydroxy-α-toxicarol () were isolated as new compounds.

Xanthones from the latex and twig extracts of Planch. ex T. Anderson (Clusiaceae) and their antidiabetic and cytotoxic activities.

A new geranylated xanthone, nigrolineaxanthone AA () together with 18 known compounds (-) were isolated from latex and twig extracts of Planch. ex T. Anderson.

Special Thai Oolong Tea: Chemical Profile and Antidiabetic Activities.

Special Thai oolong tea is oolong tea ( (L.) Kuntze) steamed with selected Thai botanical drugs. Oolong tea steamed with ginger (), lemongrass (), and celery ( L.

-Glucosidase inhibitory and -amylase inhibitory activities of compounds isolated from Blume.

A new -benzylated flavone, uvariaruflavone (), along with 13 known compounds (-) were isolated from the twig and leaf extracts of Blume. Their structures were established by extensive spectroscopic methods. Flavones (-) and cyclohexene () were isolated from for the first time.

Chemical composition, antioxidant, and antimicrobial activity of Elsholtzia beddomei C. B. Clarke ex Hook. f. essential oil.

The essential oil of Elsholtzia beddomei C. B. Clarke ex Hook.