Publications by authors named "Pablo Mesa-Del-Castillo Bermejo"
Objectives: To measure regulatory T cell (Treg) levels in the peripheral blood of children with juvenile idiopathic arthritis (JIA) and analyse the association of this measure with disease activity, quality of life, adjustment of treatment, and hospitalisation.
Methods: We conducted a two-phase study (cross-sectional and prospective), including consecutive children with a JIA diagnosis according to ILAR criteria. Our independent variables were Tregs, Th1, Th2, and cytokines in peripheral blood, and our dependent variables in the cross-sectional phase were arthritis category, JIA activity, and patient-reported outcomes.
Article Synopsis
- This study investigates the prevalence of autoimmune diseases (ADs) in parents of children with juvenile idiopathic arthritis (JIA) and highlights that these rates are higher compared to the general population.* -
- Researchers analyzed data from 8,673 JIA patients and found common familial ADs like psoriasis and rheumatoid arthritis, with familial history linked to specific factors such as older age at JIA onset and certain types of arthritis.* -
- The findings suggest that while a family history of AD increases the risk of developing JIA, it doesn't affect the severity or progression of the disease, stressing the importance of considering family health history during diagnosis.*
The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report the results of the cross-cultural adaptation and validation of the parent and patient versions of the JAMAR in the Castilian Spanish language. The reading comprehension of the questionnaire was tested in 10 JIA parents and patients.
View Article and Find Full Text PDF