Characterization of Binding Properties of Cr(Phen) and Ru(Phen) Complexes with Human Lactoferrin.

This work presents research about [Cr(phen) ] and [Ru(phen) ] interaction with human lactoferrin (HLf), a key carrier protein of ferric cations. The photochemical and photophysical properties of [Cr(phen) ] and [Ru(phen) ] have been widely studied in the last decades due to their potential use as photosensitizers in photodynamic therapy (PDT). The behavior between the complexes and the protein was studied employing UV-visible absorption, fluorescence emission and circular dichroism spectroscopic techniques.