Publications by authors named "Pablo Eiras"

Article Synopsis
  • The study investigates the issue of patients with primary biliary cholangitis (PBC) losing follow-up in the healthcare system, highlighting the negative impacts on their health outcomes.
  • An analysis of patient data from four hospitals in Spain revealed that out of 697 patients diagnosed with PBC, 14.3% were classified as lost due to lack of follow-up and treatment.
  • The research emphasizes the need to identify and re-engage these lost patients, as many are at risk of advanced liver disease, and leveraging hospital databases can help in retrieving them for necessary monitoring and treatment.
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According to new ESPGHAN guidelines, gluten challenge is considered necessary when there is doubt about the initial diagnosis of celiac disease (CD). The main aim of this study was to quantify intraepithelial lymphocyte (IEL) immunophenotype on celiac patients on gluten-containing diet (GCD) compared to those on gluten-free diet (GFD). Another aim was to evaluate the clinical utility of IELs in the CD diagnosis, especially in selected patients on GFD where diagnostic uncertainty remains.

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Malignant plasma cells (PC) from multiple myeloma (MM) patients characteristically home to the bone marrow (BM). High numbers of tumour cells are found in the peripheral blood (PB) only at end-stage disease (secondary plasma cell leukaemia, PCL) in a minority of patients. Using flow cytometric and fluorescence in situ hybridization (FISH) analysis, a high percentage of tumoral BM PC from untreated patients was found to express CD106.

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