Publications by authors named "Pablo Alvarez-Maldonado"

Purpose: To describe the clinical features and identify mortality risk factors in descending necrotizing mediastinitis (DNM) complicating deep neck abscesses (DNA) among patients admitted to the ICU.

Methods: A retrospective analysis was conducted on consecutive patients admitted to the ICU of a tertiary care public hospital. Data were collected from July 2017 to July 2024.

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Article Synopsis
  • The study aimed to analyze the clinical outcomes, comorbidities, and mortality rates of cancer patients infected with SARS-CoV-2 during the COVID-19 pandemic, along with the health protocols implemented in COVID care centers.!* -
  • Out of 1752 patients in a respiratory care unit, 5% had a prior cancer diagnosis with a distribution of 59.1% having solid tumors and 40.9% hematologic cancers; those with cancer showed lower ICU admission rates (8%) compared to non-cancer patients (17.4%).!* -
  • Despite their cancer status, hospitalized oncology patients with COVID-19 had similar survival rates as non-cancer patients, likely reflecting effective multidisciplinary care strategies
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Surgical resection of the stenotic segment with end-to-end anastomosis is considered the gold standard in postintubation tracheal stenosis. However, outcomes of this concrete aetiology are not well described. With the aim to examine the extent, range and characteristics of the existing evidence, a scoping review was performed.

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Introduction: Patients with respiratory diseases face adverse situations such as symptom management, general condition deterioration, and a hostile perception of the hospital environment, favoring the appearance of anxiety and depression.

Methods: A total of 317 patients hospitalized for a disease of pulmonary origin were analyzed and divided into the following subgroups: infectious, oncological, acute, and chronic diseases. Patients over 18 years of age with preserved cognitive capacity were included in the study.

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Objective: this study evaluated burnout symptoms among physicians and nurses before, during and after COVID-19 care.

Method: a cross-sectional comparative study in the Pulmonary Care unit of a tertiary-level public hospital. The Maslach Burnout Inventory was used.

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Extrapulmonary tuberculosis is defined as that case of tuberculosis clinically diagnosed and confirmed by bacteriological studies that affects tissues and organs outside the lung parenchyma. Mexico is in third place among Latin American countries in terms of the incidence of pulmonary and extrapulmonary tuberculosis. Culture methods are still the gold standard for the diagnosis of extrapulmonary tuberculosis since they identify the species and susceptibility to drugs.

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The clinical presentation of coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ranges between mild respiratory symptoms and a severe disease that shares many of the features of sepsis. Sepsis is a deregulated response to infection that causes life-threatening organ failure. During sepsis, the intestinal epithelial cells are affected, causing an increase in intestinal permeability and allowing microbial translocation from the intestine to the circulation, which exacerbates the inflammatory response.

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Introduction: Pulmonary aspergilloma is commonly associated with comorbidities that cause immunodeficiency such as diabetes mellitus, tuberculosis, human immunodeficiency virus/acquired immunodeficiency syndrome and/or a pre-existing parenchymal lung disease such as chronic obstructive pulmonary disease. Predisposing factors can further increase the risk of acquiring this mycosis. Our objective was to determine the frequency, clinical and microbiological characteristics of pulmonary aspergilloma in immunocompromised patients.

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Introduction: COVID-19-associated mortality in patients who require mechanical ventilation is unknown in the Mexican population.

Objective: To describe the characteristics of Mexican patients with COVID-19 who required mechanical ventilation.

Methods: Observational cohort study carried out in an intensive care unit from March 25 to July 17, 2020.

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Objective: To describe a Covid-19 outbreak in a gerontological center in Mexico City.

Material And Methods: Cross-sectional study in older adults. The association of risk factors for dying from Covid-19 was analyzed using a multiple logistic regression model.

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Background And Objectives: AKI in coronavirus disease 2019 (COVID-19) is associated with higher morbidity and mortality. The objective of this study was to identify the kidney histopathologic characteristics of deceased patients with diagnosis of COVID-19 and evaluate the association between biopsy findings and clinical variables, including AKI severity.

Design, Setting, Participants, & Measurements: Our multicenter, observational study of deceased patients with COVID-19 in three third-level centers in Mexico City evaluated postmortem kidney biopsy by light and electron microscopy analysis in all cases.

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Background: There is little information of intensive care unit (ICU) performance when it's relocated to a totally new and equipped area.

Objective: To analyze the clinical performance and use of resources of a new respiratory-ICU (nRICU) in a large third-level care hospital.

Method: Cross-sectional, comparative study using prospective data of patients admitted from July 17, 2017 to July 17, 2018.

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Introduction: New hospitals are replacing old facilities. There is little information on the performance of an intensive care unit (ICU) when it is relocated in a new and equipped area.

Objective: To analyze the impact of the change of ICU facilities from a shared environment to individual beds on the occurrence of adverse events.

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Objective: To evaluate the occurrence of adverse events during a multifaceted program implementation.

Design: Cross-sectional secondary analysis.

Setting: The respiratory-ICU of a large tertiary care center.

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Primary tracheobronchial amyloidosis (TBA) is a rare disease characterized by extracellular focal or diffuse submucosal deposits of amyloid proteins. Various types of endobronchial lesions have been described in TBA when bronchoscopy is performed using white light. Narrow-band imaging bronchoscopy has been mainly employed for detecting preneoplastic and neoplastic endobronchial lesions as it provides more detailed images of the microvasculature reflective of an altered angiogenesis process.

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Objective: To compare the results of quality monitoring after the implementation of improvement strategies in the respiratory intensive care unit (RICU).

Design: A prospective, comparative, longitudinal and interventional study was carried out.

Setting: The RICU of Hospital General de México (Mexico).

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We present the case of a 33-year-old woman who was being treated for bronchial asthma for 4 years. A tracheal tumor was evident on a computed tomography of the thorax and removed with argon plasma coagulation. It was diagnosed as pleomorphic adenoma of the trachea.

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Introduction: When compared with conventional surgery, bronchoscopy-guided percutaneous tracheostomy has demonstrated some advantages. We compare the results obtained with bronchoscopy-guided percutaneous tracheostomy performed by Intensive Care Unit personnel with those of conventional surgery.

Methods: Prospective and descriptive cohort of patients admitted to a respiratory intensive care unit from March 2010 to March 2012.

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