Publications by authors named "Pabithadevi B Mehanathan"
Article Synopsis
- Familial hypercholesterolemia (FH) is a genetic condition that causes high LDL cholesterol levels and is often not diagnosed; genetic tests can identify variants in key genes in about 80% of patients.
- A new sequencing method was developed using multiplex primers to analyze the LDLR, APOB, and PCSK9 genes, as well as specific variants related to statin effects, aiming to make the process faster, cheaper, and scalable.
- The method showed high accuracy with no variant dropouts, successfully detected known pathogenic variants, and suggested that some patients might need lower doses of statins; the entire testing process can now be done in about 3 hours for under $50.
Experience of a surgeon at the emergency department during COVID-19 pandemic.
Ann Med Surg (Lond)
December 2020
Introduction: The COVID pandemic, which started on 11th March as per the World Health Organization, has resulted in a drastic change in health care delivery, including emergency services. Most health workers have deviated towards COVID care delivery; only a few were available for non-COVID conditions. All elective and non-essential services were postponed resulting in the increased burden of the emergency department.
View Article and Find Full Text PDFIntroduction: Hashimoto's thyroiditis (HT) is a common autoimmune thyroid disorder, which predominantly presents as a diffuse goiter, with few studies which report HT presenting as multinodular goiter, with variable frequencies ranging from 59% to 78.6% especially from south Indian populations. This variant clinical presentation may have diagnostic challenges which require further analysis.
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