Towards a reduced order model for EVAR planning and intra-operative navigation.

Introduction: The pre-operative planning and intra-operative navigation of the endovascular aneurysm repair (EVAR) procedure are currently challenged by the aortic deformations that occur due to the insertion of a stiff guidewire. Hence, a fast and accurate predictive tool may help clinicians in the decision-making process and during surgical navigation, potentially reducing the radiations and contrast dose. To this aim, we generated a reduced order model (ROM) trained on parametric finite element simulations of the aortic wall-guidewire interaction.

Comparison of ultrasound vector flow imaging and CFD simulations with PIV measurements of flow in a left ventricular outflow trackt phantom - Implications for clinical use and in silico studies.

In this study we have compared two modalities for flow quantification from measurement data; ultrasound (US) and shadow particle image velocimetry (PIV), and a flow simulation model using computational fluid dynamics (CFD). For the comparison we have used an idealized Quasi-2D phantom of the human left ventricular outflow tract (LVOT). The PIV data will serve as a reference for the true flow field in our setup.

The effect of chordae tendineae on systolic flow.

When using Computational Fluid Dynamics to simulate ventricular blood flow in the heart, it has been common practice to neglect the effect of the sub-valvular apparatus and the trabeculae on the flow conditions. In this study, we analyze the effect of neglecting the chordae tendineae on the fluid flow and pressure drop. To test the assumption we use a previously developed dynamic 3D model of the left ventricle, aorta and valves that is based on 3D echocardiographic recordings.