Non-encapsulated Trichinella spp., T. papuae, diminishes severity of DSS-induced colitis in mice.

Background: Helminths use various mechanisms to avoid host immunity and protect themselves from being eliminated. Despite evading host immune responses, immunosuppression and regulation mechanisms elicit functions that diminish the adverse effects of unrelated inflammatory diseases.

Objective: We investigated whether helminthic infections can ameliorate inflammatory diseases.