Hybrid wavelet-gene expression programming and wavelet-support vector machine models for rainfall-runoff modeling.

It is critical to use research methods to collect and regulate surface water to provide water while avoiding damage. Following accurate runoff prediction, principled planning for optimal runoff is implemented. In recent years, there has been an increase in the use of machine learning approaches to model rainfall-runoff.

Design, synthesis, and discovery of novel non-peptide inhibitor of Caspase-3 using ligand based and structure based virtual screening approach.

Caspase-3 belonging to a family of cysteine proteases is main executioner of apoptotic cascade pathway. The inhibitors of this protein are useful in the treatment of cardiomyopathy and neurodegenerative diseases. For the discovery of novel Caspase-3 non-peptide inhibitors from Maybridge database, ligand based and structure based virtual screening methods were used.