Publications by authors named "PESTALOZZA G"

Habitual snoring and obstructive sleep apnea syndrome (OSA) in children are important in determining disturbed sleep, daytime symptoms and haemodynamic modifications. Moreover, chronic snoring is often associated with enlarged tonsils and adenoids. We studied 60 children (mean age 42.

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The Rubinstein-Taybi syndrome is characterized by a pattern of malformations including broad thumbs and big toes, microcephaly, facial dysmorphism, small stature, and mental retardation. Obstructive sleep apnea (OSA), has been described in several facial or skeletal malformations, but never in the Rubinstein-Taybi syndrome. We studied a 9-year-old boy, previously diagnosed as having the Rubinstein-Taybi syndrome and affected by severe OSA, as documented by polysomnography.

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Azithromycin is a newly developed azalide antibiotic which is very active against microbes causing respiratory tract infections; tissue concentrations remain elevated for a long time after discontinuation of treatment. A clinical study was conducted to compare azithromycin (10 mg/kg administered as a single daily dose for 3 days) with amoxycillin/clavulanic acid (50 mg/kg/day given b.i.

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The long term results are reported of transtympanic drains in 391 ears of 258 children affected by serous otitis; 150 ears have been evaluated at the end of a 3-7-year observation period. (1) A high percentage of ears with major anatomical lesions was found (46.6%), especially in the higher age group (greater than 7 years).

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The authors report tympanometric findings in normal newborns and infants (W-shaped, large smooth-notched curves), comparing them with those obtained in 34 ears of infants aged 5-120 days with middle ear pathology. In most cases a large smooth-notched curve was found, both in cases of serous otitis or purulent otitis. The W-shaped curve was present only in the case of normal middle ear condition.

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