Self-Assembled Nanoflowers from Natural Building Blocks with Antioxidant, Antibacterial, and Antibiofilm Properties.

Polyphenols, natural compounds abundant in phenolic structures, have received widespread attention due to their antioxidant, anti-inflammatory, antibacterial, and anticancer properties, making them valuable for biomedical applications. However, the green synthesis of polyphenol-based materials with economical and environmentally friendly strategies is of great significance. In this study, a multifunctional wound dressing was achieved by introducing polyphenol-based materials of copper phosphate-tannic acid with a flower-like structure (Cu-TA NFs), which show the reactive oxygen species scavenging performance.

Business, Human Rights and Climate Change: The Gradual Expansion of the Duty of Care.

This article investigates how human rights considerations are increasingly shaping tort law by focusing on the gradual expansion of the duty of care in business and human rights cases. For decades, victims have attempted to hold parent companies to account for extraterritorial human rights abuses committed by their foreign subsidiaries. Recently, the Supreme Court ruled that UK courts have jurisdiction over such business and human rights cases.

Implant-Supported Vertical Soft Tissue Augmentation for Severe Hard and Soft Tissue Deficiencies at Malpositioned Implants: A Case Report of a Mucogingival and Restorative Approach.

The management of severe mucogingival deformities surrounding malpositioned implants represents a complex issue with a high risk of aesthetic failure. The present case report describes a mucogingival and restorative approach for the treatment of severe localized peri-implant tissue deficiencies with interproximal bone loss combined with an interproximal gingival recession on the adjacent natural tooth. This consists of maintaining a non-restorable malpositioned implant, submerging it through one or multiple vertical soft tissue augmentations, according to the defect severity, and delivering a tooth supported bridge involving the adjacent natural teeth.

The retrograde effects of negative emotion on memory for conceptually related events: a registered report.

Emotional events are often remembered better than neutral ones; however, emotion can also spill over and affect our memory for neutral experiences that precede an emotional event. Theories suggest that emotion can retroactively enhance memory for preceding neutral events that are considered high-priority while impairing memory for events deemed low-priority. However, the impact of conceptual relationships (i.

Social cues tip the scales in emotional processing of complex pictures.

Perception of a picture is influenced by the social information and emotional value it carries for the viewer. There are still many unanswered questions about how social and emotional processing are related, but it is clear they involve overlapping brain areas and are cognitively interconnected. Yet studies of emotion processing using standardized picture datasets typically leave the social content in the pictures free to vary.

Harvest of epithelialized gingival grafts without application of hemostatic sutures: A randomized clinical trial using laser speckle contrast imaging.

Background: This randomized controlled trial with two parallel arms and a 1:1 allocation ratio aimed to compare early microvascular healing (primary outcome), surgical times, and patient-reported outcomes (PROM) after harvesting palatal epithelialized gingival grafts (EGG), where hemostasis was achieved with sutures and hemostatic sponges (control) or with a sutureless approach (test).

Methods: From a total of 33 patients, 34 EGG were harvested. Thirty-two were randomized to the test/control group (n = 16) and two were excluded.

Are autistic traits associated with a social-emotional memory bias?

Autistic traits are associated with differential processing of emotional and social cues. By contrast little is known about the relationship of autistic traits to socio-emotional memory, though research suggests an integral relationship between episodic memory processes and psychosocial well-being. Using an experimental paradigm, we tested if autistic traits moderate the effects of negative emotion and social cues on episodic memory (i.

Collaborative imagination synchronizes representations of the future and fosters social connection in the present.

From close friends to people on a first date, imagining a shared future appears fundamental to relationships. Yet, no previous research has conceptualized the act of imagination as a socially constructed process that affects how connected we feel to others. The present studies provide a framework for investigating imagination as a collaborative process in which individuals cocreate shared representations of hypothetical events-what we call collaborative imagination.

The relationship between environmentally induced emotion and memory for a naturalistic virtual experience.

Emotional stimuli (e.g. words, images) are often remembered better than neutral stimuli.

Indoxyl sulphate-initiated activation of cardiac fibroblasts is modulated by aryl hydrocarbon receptor and nuclear factor-erythroid-2-related factor 2.

In the last decade, extensive attention has been paid to the uremic toxin indoxyl sulphate (IS) as an inducer of cardiac fibroblast (cFib) activation and cardiac fibrosis in chronic kidney disease. At cellular level, IS engages aryl hydrocarbon receptor (AhR) and regulates many biological functions. We analysed how AhR inhibition by CH-223191 (CH) and overexpression of non-functional (dominant negative, DN) nuclear factor-erythroid-2-related factor 2 (NRF2), a transcription factor recruited by AhR, modulate the response of neonatal mouse (nm) cFib to IS.

The effects of emotion on retrospective duration memory using virtual reality.

Our memories for temporal duration may be colored by the emotions we experience during an event. While emotion generally enhances some aspects of memory, temporal duration has been shown to be particularly susceptible to emotion-induced distortions. However, prior work has faced difficulty when studying this phenomenon, having to make some trade-offs on ecological validity or experimental control.

The shared and unique neural correlates of personal semantic, general semantic, and episodic memory.

One of the most common distinctions in long-term memory is that between semantic (i.e., general world knowledge) and episodic (i.

Fade In, Fade Out: Do Shifts in Visual Perspective Predict the Consistency of Real-World Memories?

Memories of our personal past are not exact accounts of what occurred. Instead, memory reconstructs the past in adaptive-though not always faithful-ways. Using a naturalistic design, we asked how the visual perspective adopted in the mind's eye when recalling the past-namely, an "own eyes" versus "observer" perspective-relates to the stability of autobiographical memories.

Emotion in the mind's eye: Imagination for adaptive cognition.

In a complex world, we are constantly faced with environmental stimuli that shape our moment-to-moment experiences. But just as rich and complex as the external world is the internal milieu-our imagination. Imagination offers a powerful vehicle for playing out hypothetical experiences in the mind's eye.

Hard and soft tissue healing around teeth prepared with the biologically oriented preparation technique and restored with provisional crowns: An in vivo experimental investigation.

Aim: To evaluate the hard and soft tissues healing around teeth prepared with the biologically oriented preparation technique (BOPT) versus the chamfer technique versus non-prepared teeth.

Materials And Methods: Thirty-two teeth in eight beagle dogs were randomly prepared with the BOPT (test = 16) or chamfer (control = 16) techniques and covered with polymethylmethacrylate crowns as provisional restorations. Sixteen negative controls (non-prepared teeth) were also used for comparison.

Engineering of poly(caprolactone) and poly(glycerol sebacate) small-diameter vascular prosthesis with quercetin.

The fabrication of biodegradable, bioabsorbable, and biocompatible vascular scaffolds with enhanced mechanical and biological properties that are able to modulate local inflammation and induce endothelialization after surgical implant is still a challenge. In this work, a fibrous scaffold, made of poly(ε-caprolactone) and poly(glycerol sebacate), was fabricated to be potentially used as a small-diameter graft in vascular surgery. The novelty of this research is represented by the direct incorporation of quercetin, a well-known antioxidant compound with several biological properties, into a polymeric scaffold obtaining a vascular construct able to modulate two key factors involved in postsurgical inflammation, matrix metalloproteinase-9 and endothelial nitric oxide synthase.

Endovascular aortic repair impact on myocardial contractility: A prospective study.

Background: This study aimed to estimate if the altered sphygmic wave transmission may affect the left ventricular (LV) contractile function in patients undergoing endovascular aortic repair (EVAR).

Methods: A prospective single-centre study was carried out on consecutive patients undergoing EVAR for abdominal aortic aneurysm. A preoperative and 6-month single photon emission computed tomography (SPECT) with arterial stiffness measurement were performed to evaluate variations in pressure wave curve and myocardial perfusion parameters.

Verbal recall in amnesia: Does scene construction matter?

The hippocampus plays a critical role in episodic memory and imagination. One theoretical model posits that the hippocampus is important for scene construction, namely, the ability to conjure and maintain a scene-based representation in one's mind. To test one idea put forth by this view, we examined whether amnesia is associated with more severe impairment in memory when the to-be-remembered content places high demands on scene construction.

Techniques on vertical ridge augmentation: Indications and effectiveness.

Vertical ridge augmentation techniques have been advocated to enable restoring function and esthetics by means of implant-supported rehabilitation. There are three major modalities. The first is guided bone regeneration, based on the principle of compartmentalization by means of using a barrier membrane, which has been demonstrated to be technically demanding with regard to soft tissue management.

Minimal invasiveness in vertical ridge augmentation.

Vertical ridge augmentation is one of the most challenging procedures in implant dentistry because of the advanced skills required by the operator and the fact that bone augmentation is aimed outside the bony contour, in an environment of reduced blood supply. What is more, the flap management required to ensure soft tissue closure frequently leads to associated comorbidities in terms of swelling and hematomas. For these reasons, and even if autologous onlay block grafts are still the gold standard, new techniques and biomaterials have favored the development of potentially less invasive approaches.

Brief diesel exhaust exposure acutely impairs functional brain connectivity in humans: a randomized controlled crossover study.

Background: While it is known that exposure to traffic-related air pollution causes an enormous global toll on human health, neurobiological underpinnings therein remain elusive. The study addresses this gap in knowledge.

Methods: We performed the first controlled human exposure study using functional MRI with an efficient order-randomized double-blind crossover study of diesel exhaust (DE) and control (filtered air; FA) in 25 healthy adults (14 males, 11 females; 19-49 years old; no withdrawals).