THE INCIDENCE OF COMORBID MENTAL AND PHYSICAL CONDITIONS IN PATIENTS WITH POST-TRAUMATIC STRESS DISORDER.

There is a small body of research about mental and physical comorbidity in post-traumatic stress disorder (PTSD) patients despite the fact that some psychiatric disorders and physical conditions are commonly comorbid with PTSD. In this study, we researched the relationship between PTSD and its mental and physical comorbidities by comparing the number of patient hospitalizations across two ten-year periods. Our sample consisted of 2761 patients with warfare PTSD hospitalized during the 20-year period (1999-2018).

PTSD Symptoms and Coping with COVID-19 Pandemic among Treatment-Seeking Veterans: Prospective Cohort Study.

Background: The aim of this study was to examine post-traumatic stress disorder (PTSD) symptom levels and coping strategies during the COVID-19 pandemic among treatment-seeking veterans with pre-existing PTSD.

Method: A cohort of 176 male treatment-seeking veterans with pre-existing PTSD during the first COVID-19 pandemic lockdown (T1) and 132 participants from the same cohort one year after the onset of the pandemic (T2) participated in a longitudinal study. All participants responded to a COVID-19-related questionnaire and the following measures: the Life Events Checklist for DSM-5 (LEC-5), PTSD Checklist for DSM-5 (PCL-5) and the Brief COPE.

Effect of colchicine on angiotensin receptors in rabbit aorta.

Colchicine (10(-5) M) significantly depressed the dose-response curve for angiotensin in isolated rabbit aortic strips. A lower maximal response was observed without apparent change in receptor affinity for angiotensin, as can be judged by unchanged ED50 values. Colchicine also diminished the dose-response curve for norepinephrine.

Separation of angiotensin receptor from cell membrane angiotensinase in rabbit aorta.

Deoxycholic acid (0.01%) diminished the tissue response to angiotensin in rabbit aortic strips. A lower maximal response was obtained, but the affinity of angiotensin receptors did not change.

Angiotensinase activity and angiotensin receptor binding in guinea pig aorta.

The angiotensinase (EC 3.4.99.

Characterization of the angiotensin receptor in guinea-pig aorta.

The binding of 14C-angiotensin to the subcellular fractions of guinea-pig aorta was compared to the known physiological data as obtained from the intact preparation. Results show that only the plasma membrane fraction possesses binding characteristics consistent with the physiological data. Equilibrium of specific binding occurs at 10(-7) M 14C-angiotensin which is the physiological maximal dose.