Publications by authors named "P-E Falcoz"
Article Synopsis
- Non-small cell lung cancer (NSCLC) often leads to compromised lung function, and this study focuses on the effects of surgical methods, specifically minimally invasive surgery (MIS), on 90-day post-operative mortality in high-risk patients.
- The research analyzed data from over 46,000 patients, identifying high-risk individuals with poor lung function, and found a significantly higher mortality rate in this group compared to low-risk patients.
- Results indicated that high-risk patients undergoing MIS had lower mortality rates than those undergoing traditional open surgery, even matching the mortality rates of low-risk patients.
This work describes a patient-derived tumoroid model (PDTs) to support precision medicine in lung oncology. The use of human adipose tissue-derived microvasculature and patient-derived peripheral blood mononuclear cells (PBMCs) permits to achieve a physiologically relevant tumor microenvironment. This study involved ten patients at various stages of tumor progression.
View Article and Find Full Text PDFThe anti-tumour and anti-metastatic properties of heparins have not been tested in patients with early stage cancer. Whether adjuvant low molecular weight heparin (LMWH) tinzaparin impacts the survival of patients with resected non-small cell lung cancer (NSCLC) was investigated.Patients with completely resected stage I, II or IIIA NSCLC were randomly allocated to receive subcutaneous tinzaparin 100 IU·kg once a day for 12 weeks or no treatment in addition to standard of care.
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