Publications by authors named "P jansa"

Hybrid sterility is a reproductive isolation barrier between diverging taxa securing the early steps of speciation. Hybrid sterility is ubiquitous in the animal and plant kingdoms, but its genetic control is poorly understood. In our previous studies, we have uncovered the sterility of hybrids between musculus and domesticus subspecies of the house mouse, which is controlled by the Prdm9 gene, the X-linked Hstx2 locus, and subspecific heterozygosity for genetic background.

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  • * This study aimed to explore long-term pulmonary perfusion issues in COVID-19 survivors who experienced severe acute respiratory distress syndrome (ARDS) and were treated with ECMO at a specific institution.
  • * Out of 80 patients who survived ECMO treatment, only 37 were analyzed; while VTE occurred frequently during acute illness, no ongoing pulmonary perfusion abnormalities were found after an average of 14 months post-ECMO.
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Introduction: Chronic thromboembolic pulmonary hypertension (CTEPH) and venous thromboembolism (VTE) are thought to share many common risk factors. Our study aimed to determine the frequencies of 5 thrombosis-related gene single nucleotide polymorphisms (SNPs) associated with VTE in patients with CTEPH (n 129) compared with a control group of healthy individuals without a history of VTE (n 2637).

Methods: The SNPs of the following genes were investigated: (F V Leiden, rs6025), prothrombin (rs1799963), fibrinogen gamma (FGG, rs2066865), (rs2289252) and (non-O, rs8176719) in both groups.

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  • Supraventricular tachycardia (SVT), a common issue for patients with pulmonary hypertension (PH), includes conditions like atrial fibrillation and atrial flutter, which can worsen heart function.
  • Restoring normal heart rhythm through methods like catheter ablation can lead to improvements, though long-term success is challenged by the potential for arrhythmia recurrence.
  • Catheter ablation is generally effective for less complex SVTs, but its use for complex cases like atrial fibrillation needs to be more tailored due to higher risks and varying outcomes.
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