Proteomics and recurrence of atrial fibrillation: a pilot study nested in the PREDIMAR trial.

Introduction: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia worldwide. Although catheter ablation is the most efficacious therapy, relapses occur frequently (30%) in the first year after ablation. Novel biomarkers of recurrence are needed for a better prediction of recurrence and management of AF.

Temperament Upregulates Mitochondrial Enzymes and Negatively Affects Myofibrillar Fragmentation in Beef of Excitable Cattle.

Background: cattle is known to be temperamental and to produce beef with greater variability in terms of quality compared to beef of . Cattle adaptability and resilience are of great importance to sustain beef production worldwide.

Objective: The study aimed to understand early post-mortem metabolites among muscles with different fiber types profile of calm and excitable Nellore, as well as its relationship with fragmentation of beef aged up to 28 d.

Breaking research silos to achieve equitable precision medicine in rheumatology.

Health disparities in rheumatic disease are well established and urgently need addressing. Obstacles to precision medicine equity span both the clinical and the research domains, with a focus placed on structural barriers limiting equitable health care access and inclusivity in research. Less articulated factors include the use of inaccurate population descriptors and the existence of research silos in rheumatology research, which creates a knowledge gap that precludes addressing the health disparities and fulfilling the goals of precision medicine to understand the 'full patient'.

Early warning system using primary health care data in the post-COVID-19 pandemic era: Brazil nationwide case-study.

Syndromic surveillance using primary health care (PHC) data is a valuable tool for early outbreak detection, as demonstrated by the potential to identify COVID-19 outbreaks. However, the potential of such an early warning system in the post-COVID-19 era remains largely unexplored. We analyzed PHC encounter counter of respiratory complaints registered in the database of the Brazilian Unified National Health System from October 2022 to July 2023.

Estimation of Genetic Parameters and GWAS on Water Efficiency Traits in the Senepol Cattle.

The need for producing in environmentally resilient system drives new research to achieve sustainable beef production. Water footprint of the beef supply chain is a concern that must be addressed, aiming to improve water use within the production chain. One approach is genetic selection of beef cattle for water efficiency.