Publications by authors named "P de Cosmo"
Objective: Clinical decision support systems (CDSSs) can reduce medical errors increasing drug prescription appropriateness. Deepening knowledge of existing CDSSs could increase their use by healthcare professionals in different settings (ie, hospitals, pharmacies, health research centres) of clinical practice. This review aims to identify the characteristics common to effective studies conducted with CDSSs.
View Article and Find Full Text PDFImmunohistochemical demonstration of neuroendocrine differentiation is often performed in routine diagnostic practice for lung neuroendocrine carcinoma. However, these carcinomas are often crushed, especially on small specimens. The value of immunohistochemistry on crushed areas is not known.
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- The study aimed to analyze the proteins in vestibular schwannoma (VS), non-vestibular schwannoma (NVS), and normal nerve (NN) using advanced techniques like mass spectrometry and MALDI-TOF imaging.
- Samples were collected retrospectively from a Tumor Bank, processed using histological examination, and analyzed for peptide content, revealing varying correlations between imaging and pathology results.
- The findings indicated that while NVS and NN showed stronger correlations between MALDI-imaging and histological results, vestibular schwannomas, particularly of the Antoni type A, had a high lack of correspondence, highlighting the complexities in analyzing these tumors.
Background: The absence of collaboration between health professionals is known to influence prescriptions' quality, also disadvantaging elderly frail patients' polytherapies.
Objectives: This study aims to improve the adherence to medications of elderly patients suffering from multiple diseases through interpersonal continuing medical education (CME). The CME was organized for general practitioners (GPs) by hospital pharmacists (HPs) from a Territorial Pharmaceutical Centre of Piedmont, in collaboration with pharmacists from the Drug Science and Technology Department of the University of Turin, to enhance awareness on the management of chronic therapies and de-prescription.
Background: Soft tissue fillers are usually identified in the skin using the conventional histopathologic examination. Ex vivo RCM has been used in one case and Raman spectroscopy (RS), which has been recently applied for the identification of skin foreign bodies, has never been employed for fillers. We report the use of both these new techniques, ex vivo RCM and RS, to confirm the diagnosis of adverse reaction to a soft tissue filler and to identify its composition.
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