Post-herpes neurotrophic keratopathy: Aetiopathogenesis, clinical signs and current therapies.

Neurotrophic keratopathy (NK) is a degenerative corneal disease caused by damage of trigeminal innervation. This leads to epithelial defects, ulceration and, eventually, perforation. Both herpes simplex and varicella zoster keratitis are reported to be the main causes of NK.

Treatment with platelet-rich plasma of surgically related dormant corneal ulcers.

Purpose: To assess the effectiveness of autologous platelet-rich plasma for the treatment of dormant corneal ulcers secondary to corneal surgery and unresponsive to conventional treatment.

Setting: VISSUM, Ophthalmology Institute of Alicante, Alicante, Spain.

Design: Prospective nonrandomized, observational consecutive study.