Alterations of non-motor symptoms in Parkinson's disease, after of subthalamic deep brain stimulation.

Unlabelled: The effect of subthalamic deep brain stimulation (STN DBS) on motor symptoms of Parkinson's disease (PD) has been thoroughly analyzed. The influence of STN DBS on non-motor symptoms (NMS) is still debatable. We analyzed the effect of STN DBS on NMS in PD.

Periaqueductal/periventricular gray deep brain stimulation for the treatment of neuropathic facial pain.

Background: The Periaqueductal gray (PAG) and the periventricular gray (PVG) are the anatomical targets for deep brain stimulation (DBS) to treat severe, refractory neuropathic pain.

Methods: Seven (four female and three male) patients were qualified for PAG/PVG DBS because of neuropathic facial pain. Frame-based unilateral implantations of DBS were conducted according to indirect planning of the PAG/PVG, contralateral to reported pain (3389, Activa SC 37603, Medtronic).

[Idiopathic retroperitoneal fibrosis--the Ormond's disease].

Idiopathic retroperitoneal fibrosis, so called "Ormond's disease" belongs to rare inflammatory processes of unknown etiology. As a result of this disease fibrotic masses causing compression of the ureters, vessels and alimentary canal appear in the retroperitoneal space. In this study we describe the case of 59 years old man.

[CT colonography--a new method in the diagnosis of the colon].

CT colonography--the method of examination of the colon with spiral computed tomography--was presented. Examination technique, its clinical application and current position among other diagnostic examinations of the large bowel, as well as further development of the method were described.

Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class.

Glioblastoma multiforme is the most common primary human brain tumor, and it is, for all practical purposes, incurable in adult patients. The high mortality rates reflect the fact that glioblastomas are resistant to adjuvant therapies (radiation and chemicals), the mode of action of which is cytotoxic. We show here that an p.