Publications by authors named "P Younes"
Introduction: Intervertebral discs are part of the vertebral column and are considered the pads that help in cushioning and flexibility. These discs consist of nucleus pulposus, annulus fibrosus, and cartilage end plate and their major functions include spinal motion and loading. However, they are prone to numerous pathologies such as intradiscal hematoma and discal cyst formation that may significantly alter the biomechanics of the spine and hence the quality of life of the patient.
View Article and Find Full Text PDFDiffuse large B cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma and the most frequently diagnosed hematologic malignancy in the United States. DLBCL exhibits significant molecular and clinical heterogeneity, and at least a third of patients are left uncured with standard frontline chemoimmunotherapy. As such, there is a critical need to identify novel targeted therapies to improve outcomes.
View Article and Find Full Text PDFA ganglioglioma versus a schwannoma: Which is in the sacral spine?
Int J Surg Case Rep
November 2024
Article Synopsis
- - The text discusses sacral spinal gangliogliomas, rare tumors that can cause symptoms like lower back pain and bladder issues, and are treated primarily through surgical resection due to their location near critical nerves.
- - A case study of a 66-year-old woman highlights the surgical challenges faced, where a misdiagnosis led to unexpected findings during surgery but ultimately resulted in successful near-total tumor removal and symptom relief.
- - The conclusion emphasizes the need for accurate diagnosis and careful surgical planning to minimize neurological risks, and it calls for ongoing research to enhance treatment strategies for these tumors.
Background: Listeria monocytogenes brain abscess is a rare phenomenon that is common in immunocompromised patients. Streptococcus equinus brain abscess has never been reported in the literature to our knowledge. In this case report, we describe a case of brain abscess secondary to Listeria monocytogenes and Streptococcus equinus in an immunocompetent patient with transient low CD4 count.
View Article and Find Full Text PDFArticle Synopsis
- The occurrence of Down syndrome and Dandy-Walker syndrome together is rare, with only four documented cases, all involving very young children with poor outcomes.
- This report presents a unique case of an 11-year-old male who had Dandy-Walker syndrome undiagnosed until he experienced acute intracranial hypertension, which was treated successfully.
- The findings suggest that an asymptomatic young patient can have both conditions, and that effective treatments exist for managing complications like hydrocephalus associated with Dandy-Walker malformation.