Publications by authors named "P Y Daoust"
Wastewater-based surveillance (WBS) is increasingly used for monitoring disease targets in wastewaters around the world. This study, performed in Ottawa, Canada, identifies a decrease in SARS-CoV-2 wastewater measurements during snowmelt-induced sewer flushing events. Observations first revealed a correlation between suppressed viral measurements and periods of increased sewage flowrates, air temperatures above 0 °C during winter months, and solids mass flux increases.
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- The study investigates the decay patterns of SARS-CoV-2 and Pepper mild mottle virus (PMMoV) in wastewater contaminated with stool samples from COVID-19 patients, aiming to reflect real-world conditions better than traditional laboratory methods.
- It examines how these viruses decay under two specific sewer transport conditions—dynamic suspended transport and bed/near-bed transport—across varying temperatures (4°C, 12°C, and 20°C).
- Results show no significant decay of SARS-CoV-2 or PMMoV in dynamic suspended transport over 35 hours, while significant decay occurs in bed/near-bed conditions, especially for PMMoV, which shows higher decay rates at elevated temperatures.
Wastewater-based surveillance of human disease offers timely insights to public health, helping to mitigate infectious disease outbreaks and decrease downstream morbidity and mortality. These systems rely on nucleic acid amplification tests for monitoring disease trends, while antibody-based seroprevalence surveys gauge community immunity. However, serological surveys are resource-intensive and subject to potentially long lead times and sampling bias.
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- * The manuscript details a dataset collected from January 2021 to March 2023, including RT-qPCR results from 107 sites, with data covering a significant portion of Ontario's population.
- * This initiative has been vital for public health as it provides crucial information for monitoring disease trends, particularly during the rise of the Omicron variant, and emphasizes the importance of wastewater surveillance in understanding disease incidence.