Direct Water-Assisted Laser Desorption/Ionization Mass Spectrometry Lipidomic Analysis and Classification of Formalin-Fixed Paraffin-Embedded Sarcoma Tissues without Dewaxing.

Background: Formalin-fixed paraffin-embedded (FFPE) tissue has been the gold standard for routine pathology for general and cancer postoperative diagnostics. Despite robust histopathology, immunohistochemistry, and molecular methods, accurate diagnosis remains difficult for certain cases. Overall, the entire process can be time consuming, labor intensive, and does not reach over 90% diagnostic sensitivity and specificity.

Fate and impact of pesticides applied to potato cultures: the Nicolet River basin.

The fate of cash-crop (potato) pesticides was monitored from the fields on which they were applied to the nearby streams. The investigation took place in the Nicolet River basin in the province of Quebec, Canada. The main pesticides under study were aldicarb, fenvalerate, metribuzin, and phorate.

Comparative study of the effects of MCPA, butylate, atrazine, and cyanazine on Selenastrum capricornutum.

The herbicides MCPA, butylate, atrazine and cyanazine are extensively used in Canadian agriculture and information regarding their effects on indigenous biota is scarce. Phytotoxicity assessments were conducted in the laboratory on the common green alga Selenastrum capricornutum using both the active ingredient of the herbicides and their formulated products (for MCPA and butylate). Endpoints determined after the 96 h exposure included algal population growth inhibition (IC50-cell counts), percent lethality (LC50-flow cytometry derived) and photosynthetic electron transport inhibition (EC50-fluorescence induction).

Lemna minor membranes affected by adjuvants.

The perturbant effects of four Triton adjuvants, namely Triton X-15, X-35, X-100, and X-114 (alkyl aryl polyether alcohols), on some of the biochemical determinants of membrane integrity were determined under laboratory conditions. Two of these, Triton X-100 and X-114, are currently being assessed as emulsifiers for use in fenitrothion insecticidal formulations. Lemna minor L.