Publications by authors named "P Wuchter"
Article Synopsis
- Major ABO-incompatible hematopoietic stem cell transplantation (allo-HCT) can lead to serious complications, including prolonged thrombocytopenia and increased need for platelet transfusions due to persistent anti-donor isoagglutinins.
- A 55-year-old male with chronic myelomonocytic leukemia experienced significant transfusion reactions after receiving A Rh(D)-negative platelets following his major incompatible allo-HCT.
- Modifying his platelet transfusion strategy to include only O Rh(D)-negative donors effectively reduced transfusion needs and eliminated reactions, highlighting the importance of isoagglutinin monitoring.
Purpose: Mesenchymal stromal cells (MSCs) within the glioblastoma microenvironment have been shown to promote tumor progression. Tumor Treating Fields (TTFields) are alternating electric fields with low intensity and intermediate frequency that exhibit anti-tumorigenic effects. While the effects of TTFields on glioblastoma cells have been studied previously, nothing is known about the influence of TTFields on MSCs.
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