Publications by authors named "P Weisburd"

Percutaneous pulmonary valvuloplasty was performed successfully in two neonates with cyanotic tetralogy of Fallot. It seems that balloon valvotomy may represent a palliative therapeutic alternative of choice in the neonatal period.

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Article Synopsis
  • Three premature babies exposed in utero to prostaglandin synthetase inhibitors (PSI) and corticosteroids experienced renal dysfunction at birth.
  • One infant had transient water and sodium retention leading to uraemia, while twins suffered from severe acute renal failure and high potassium levels (hyperkalaemia).
  • The renal issues may stem from disrupted prostaglandin-mediated adaptation to stress due to PSI exposure, and the corticosteroids could have played a role in inhibiting prostaglandin synthesis.
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In spite of the prominent position reached by echocardiography in the anatomical and functional diagnosis of congenital heart disease, angiography remains the reference method for preoperative assessment of most cardiovascular malformations. Digitalization of angiographic images, recently applied to cardiology, is of particular interest in paediatrics: the versatility of the method, the smaller amount and dilution of the contrast medium, the diminution of catheter size and the shorter exposure to X-rays are factors that reduce the risk of this invasive investigation. The experience acquired by the exploration of 500 congenital heart disease shows that there is no technical obstacle to using this method in paediatric cardiology, especially since the images obtained clearly are of better quality.

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