Coswara: A respiratory sounds and symptoms dataset for remote screening of SARS-CoV-2 infection.

This paper presents the Coswara dataset, a dataset containing diverse set of respiratory sounds and rich meta-data, recorded between April-2020 and February-2022 from 2635 individuals (1819 SARS-CoV-2 negative, 674 positive, and 142 recovered subjects). The respiratory sounds contained nine sound categories associated with variants of breathing, cough and speech. The rich metadata contained demographic information associated with age, gender and geographic location, as well as the health information relating to the symptoms, pre-existing respiratory ailments, comorbidity and SARS-CoV-2 test status.

Proprioceptive neuromuscular facilitation training reduces pain and disability in individuals with chronic low back pain: A systematic review and meta-analysis.

Background: and purpose: Although proprioceptive neuromuscular facilitation (PNF) exercises are used in rehabilitation practice, their effects in patients with low back pain (LBP) remain unclear. This study aimed to investigate the efficacy of PNF training for pain and disability in patients with LBP.

Methods: In this systematic review, we searched five databases from the earliest date available to October 2020.

Finding water scarcity amid abundance using human-natural system models.

Water scarcity afflicts societies worldwide. Anticipating water shortages is vital because of water's indispensable role in social-ecological systems. But the challenge is daunting due to heterogeneity, feedbacks, and water's spatial-temporal sequencing throughout such systems.

Combined statin and angiotensin-converting enzyme (ACE) inhibitor treatment increases the lifespan of long-lived F1 male mice.

Statins, such as simvastatin, and ACE inhibitors (ACEis), such as ramipril, are standard therapies for the prevention and treatment of cardiovascular diseases. These types of drugs are commonly administered together. More recently, angiotensin II type 1 receptor (AT1R) antagonists, such as candesartan cilexetil (candesartan), have been used in the place of, or in combination with, ACEis.

MicroRNAs Circulate in the Hemolymph of Drosophila and Accumulate Relative to Tissue microRNAs in an Age-Dependent Manner.

In mammals, extracellular miRNAs circulate in biofluids as stable entities that are secreted by normal and diseased tissues, and can enter cells and regulate gene expression. Drosophila melanogaster is a proven system for the study of human diseases. They have an open circulatory system in which hemolymph (HL) circulates in direct contact with all internal organs, in a manner analogous to vertebrate blood plasma.