A pre-rule for the sequential probability ratio test in a between-item grid multidimensional computerized classification test.

The measurement efficiency of a grid multidimensional computerized classification test (grid MCCT), which makes a classification decision per dimension, can be improved by taking the correlations between the dimensions into account in the termination criterion. The higher the correlations, the better the improvement in measurement efficiency. However, a termination criterion utilizing inter-dimensional information (i.

Anisotropic structure of nanofiber hydrogel accelerates diabetic wound healing via triadic synergy of immune-angiogenic-neurogenic microenvironments.

Wound healing in chronic diabetic patients remains challenging due to the multiple types of cellular dysfunction and the impairment of multidimensional microenvironments. The physical signals of structural anisotropy offer significant potential for orchestrating multicellular regulation through physical contact and cellular mechanosensing pathways, irrespective of cell type. In this study, we developed a highly oriented anisotropic nanofiber hydrogel designed to provide directional guidance for cellular extension and cytoskeletal organization, thereby achieving pronounced multicellular modulation, including shape-induced polarization of macrophages, morphogenetic maturation of Schwann cells, oriented extracellular matrix (ECM) deposition by fibroblasts, and enhanced vascularization by endothelial cells.

Regional brain iron correlates with transcriptional and cellular signatures in Alzheimer's disease.

Introduction: The link between overload brain iron and transcriptional/cellular signatures in Alzheimer's disease (AD) remains inconclusive.

Methods: Iron deposition in 41 cortical and subcortical regions of 30 AD patients and 26 healthy controls (HCs) was measured using quantitative susceptibility mapping (QSM). The expression of 15,633 genes was estimated in the same regions using transcriptomic data from the Allen Human Brain Atlas (AHBA).

Physics-driven untrained neural network for vortex beam compensation in adaptive optics aided underwater wireless optical communications.

Orbital angular momentum (OAM) multiplexing is emerging as a critical technique for achieving high data capacity in underwater wireless optical communications (UWOC). Nonetheless, wavefront distortions induced by underwater turbulence compromise the orthogonality of OAM modes. In this paper, we introduce a physics-driven untrained learning approach for adaptive optics that operates independently of extensive amplitude datasets.

Zirconium-doped iron oxide nanoparticles for enhanced peroxidase-like activity.

FeO nanoparticles (NPs) have emerged as pioneering nanozymes with applications in clinical diagnosis, environmental protection and biosensing. However, it is currently limited by insufficient catalytic activity due to poor electron transfer. In this study, we synthesized electron-rich-Zr-doped defect-rich FeO NPs (ZrFeO) using a one-pot solvothermal method.