Publications by authors named "P W Estep"

Genetic screens in have long been used to identify genes found in a variety of developmental, cellular, and behavioral processes. Here we describe the characterization and mapping of a mutation identified in a conditional screen for genetic regulators of cell growth and cell division. Within a Flp/FRT system, mutant results in a reduction of mutant tissue and a rough eye phenotype.

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. Upcoming missions of the National Aeronautics and Space Administration (NASA) to the Moon will include extensive human exploration of the lunar surface. Walking will be essential for many exploration tasks, and metabolic cost during ambulation on simulated complex lunar surfaces requires further characterization.

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In order to limit the aviator's exposure to potentially unsafe helmet configurations, the U.S. Army Aeromedical Research Laboratory (USAARL) developed the USAARL Head-supported mass (HSM) Performance Curve and Acute Injury Risk Curve as guidelines for Army aviation HSM.

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Article Synopsis
  • The current method for drug discovery involves testing a variety of drug candidates on target molecules, with high-throughput kinetic measurements offering advantages in understanding binding affinity.
  • Despite advancements in technology, there are still challenges in data processing, such as inadequate models for poor-quality data, time-consuming interfaces, and lack of historical data integration.
  • The solution proposed is an automated system for analyzing, storing, and retrieving kinetic binding data, which improves data quality management and enhances the analysis of molecular interactions and competition.
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