Publications by authors named "P W De Leeuw"
Article Synopsis
- - The study investigates how the postpartum menstrual cycle influences levels of aldosterone and renin in women, comparing those with a history of preeclampsia to healthy controls, using data from 98 participants.
- - Measurements were taken during both the follicular and luteal phases of the menstrual cycle, showing elevated levels of aldosterone and renin during the luteal phase for both groups, but the aldosterone-to-renin ratio remained unchanged.
- - Findings indicate that women with recent preeclampsia have lower levels of renin, aldosterone, and the aldosterone-to-renin ratio compared to controls, with significant differences observed particularly in the follicular phase.
The Death of Pyotr Ilyich Tchaikovsky: The Result of Treatment with Arsenic?
Med Princ Pract
July 2023
No abstract applicable.
View Article and Find Full Text PDFObjective: The aldosterone-to-renin ratio (ARR) is widely used as a screening test for primary aldosteronism, but its determinants in patients with essential hypertension are not fully known. The purpose of the present investigation is to identify the impact of age, sex and BMI on renin, aldosterone and the ARR when measured under strict, standardized conditions in hypertensive patients without primary aldosteronism.
Methods: We analysed the data of 423 consecutive hypertensive patients with no concomitant cardiac or renal disorders from two different hospitals (Rotterdam and Maastricht) who had been referred for evaluation of their hypertension.
Background Salt restriction may lower blood pressure variability (BPV), but previous studies have shown inconsistent results. Therefore, we investigated in an observational study and intervention trial whether urinary sodium excretion and salt intake are associated with 24-hour BPV. Methods and Results We used data from the cross-sectional population-based Maastricht Study (n=2652; 60±8 years; 52% men) and from a randomized crossover trial (n=40; 49±11 years; 33% men).
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