Publications by authors named "P W Danse"
Patients undergoing percutaneous coronary intervention (PCI) may experience bleeding events. Bleeding risk is increased in patients with comorbid peripheral arterial disease (PADs). To evaluate whether PCI patients with PADs have worse outcome after bleeding, we assessed pooled patient-level data of 5,989 randomized all-comer trial participants and identified those who had a bleeding (BIO-RESORT:NCT01674803, BIONYX:NCT02508714).
View Article and Find Full Text PDFBackground And Objective: Evidence on health economic outcomes for percutaneous coronary intervention (PCI) comparing different contemporary drug-eluting stents (DES) with each other is scarce, as most previous randomised DES trials did not assess such aspects. This prespecified health economic evaluation of the Comparison of Biodegradable Polymer and Durable Polymer Drug-Eluting Stents in an All Comers Population (BIO-RESORT) trial aimed to compare at 3-year follow-up both health effects and costs of PCI with one of three new-generation drug-eluting stents (DES) in patients with obstructive coronary artery disease.
Methods: The randomised BIO-RESORT trial assessed in 3514 patients the ultrathin-strut biodegradable polymer Orsiro sirolimus-eluting stent (SES) and very-thin-strut Synergy everolimus-eluting (EES) stent versus the thin-strut durable polymer Resolute Integrity zotarolimus-eluting stent (ZES).
Article Synopsis
- Mortality rates in patients with cardiogenic shock due to acute myocardial infarction (AMICS) remain high, prompting research into how prehospital symptom duration affects patient outcomes.
- A study analyzed data from 1,363 AMICS patients, revealing that longer symptom durations significantly increased the 30-day mortality rates, especially for those with symptoms lasting over 24 hours.
- The findings highlight the importance of early identification and intervention, suggesting that prolonged symptoms are a strong predictor of poor survival rates in AMICS patients, particularly those receiving mechanical circulatory support.
Aims: The optimal vascular access site for percutaneous coronary interventions (PCIs) in patients with acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) remains uncertain. While observational data favour transradial access (TRA) due to lower complication rates and mortality, transfemoral access (TFA) PCI offers advantages such as shorter access and procedure times, along with quicker escalation to mechanical circulatory support (MCS). In this study, we aimed to investigate factors associated with a transfemoral approach and compare mortality rates between TRA and TFA in AMI-CS patients undergoing PCI.
View Article and Find Full Text PDFArticle Synopsis
- Ethnic minorities are at a higher risk for cardiovascular issues, but previous trials in Europe didn't consider their backgrounds when studying outcomes after coronary stenting.
- * A study analyzed data from two trials involving 5803 patients to compare outcomes in ethnic minority patients versus those of Western European origin after coronary interventions.
- * Findings showed no significant difference in 1-year complications (like target vessel failure) between ethnic minorities and Western European patients, despite ethnic minorities having worse cardiovascular risk factors.