Displays Altered Stress Responses While Enhancing Biofilm Formation by in Mixed-Species Consortium.

Like , lactobacilli are commonly isolated from carious sites, although their exact role in caries development remains unclear. This study used mixed-species models to analyze biofilm formation by major groups of oral lactobacilli, including ssp. , and .

Conservative Management of Dental Caries Using Silver Nitrate and Atraumatic Restorative Treatment in Remote Rural Setting.

Managing dental caries remains a challenge to clinicians—more so when treating caries in remote, underserved areas of the world. The purpose of this article is to report preliminary results of an effort to reduce to practice the best features of silver nitrate (SN) anti-caries effect and atraumatic restorative treatment (ART) for lesion preparation and restoration. The modifications made to two approaches have practical applications to school-based outreach programs hoping to respond to the dire need for preventive and conservative restorative methods in parts of the world where access to the dental office is unobtainable.

Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera.

Lactobacilli are a diverse group of species that occupy diverse nutrient-rich niches associated with humans, animals, plants and food. They are used widely in biotechnology and food preservation, and are being explored as therapeutics. Exploiting lactobacilli has been complicated by metabolic diversity, unclear species identity and uncertain relationships between them and other commercially important lactic acid bacteria.

Characterizing Diversity of Lactobacilli Associated with Severe Early Childhood Caries: A Study Protocol.

Lactobacilli have been consistently associated with dental caries for decades; however, knowledge of this group of bacteria in the etiology of the disease is limited to quantitative elucidation. Nowadays, explicit identification of oral species is possible, despite their taxonomic complexity. Here we describe a combined approach involving both cultivation and genetic methods to ascertain and characterize the diversity and abundance of the population in the oral cavities of children with severe early childhood caries (S-ECC).

Oral Lactobacilli and Dental Caries: A Model for Niche Adaptation in Humans.

Lactobacilli have been associated with dental caries for over a century. Here, we review the pertinent literature along with findings from our own study to formulate a working hypothesis about the natural history and role of lactobacilli. Unlike most indigenous microbes that stably colonize a host, lactobacilli appear to be planktonic, opportunistic settlers that can gather and multiply only in certain restrictive niches of the host, at least within the oral cavity.