Publications by authors named "P Vineeth"
Stimuli-responsive nanoplatforms have been popular in controlled drug delivery research because of their ability to differentiate the tumor microenvironment from the normal tissue environment in a spatiotemporally controllable manner. The synergistic therapeutic approach of combining cancer chemotherapy with photothermal tumor ablation has improved the therapeutic efficacy of cancer therapeutics. In this study, a UiO-66 metal organic framework (MOF)-based system loaded with doxorubicin (DOX), surface decorated with the photothermal agents indocyanine green (ICG) and polydopamine (PDA), and conjugated with transferrin (TF) was successfully designed to operate as a responsive system to pH changes, featuring photothermal capabilities and target specificity for the purpose of treating breast cancer.
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- MXenes are advanced 2D materials with exceptional mechanical, electrical, and thermal properties, making them significant in nanotechnology, particularly for biomedical applications like cancer treatment.
- Their unique characteristics enable MXene conjugates to be effective in anticancer therapies and offer capabilities for bioimaging and biosensing.
- The review discusses various synthesis methods, the potential benefits and risks related to toxicity, and the future challenges and opportunities for clinical use of these nanoconjugates in medicine.
Aim: Long-term outcome data of acute decompensated heart failure (HF) are scarce from India. The aim of the study was to collect in-hospital and long-term outcome data of HF patients admitted during 2001-2010 in a tertiary-care centre in South India.
Methods And Results: Consecutive patients admitted with first episode of decompensated HF were part of the registry.