Porokeratosis of Mibelli and HIV-infection.

Background: The exacerbation of porokeratosis of Mibelli associated with inmunosuppression has been well documented.

Materials And Methods: We describe the clinical and histologic data of three cases of HIV-infected patients, who developed porokeratosis following HIV-contact.

Results: The three reported patients were found to have the clinical and histologic features of porokeratosis of Mibelli.

Once-daily 0.1% mometasone furoate cream versus twice-daily 0.1% betamethasone valerate cream in the treatment of a variety of dermatoses.

A randomized, investigator-blind, parallel-group trial was conducted to compare the safety and efficacy of 0.1% mometasone furoate cream applied once daily with that of 0.1% betamethasone valerate cream applied twice daily in patients (n = 69) with allergic contact dermatitis, atopic dermatitis and other steroid-responsive dermatoses.

[Oral hairy leukoplakia].

At present HL: should be considered a marker of immunodeficiency, though not necessarily associated with HIV infection. In eight patients with HL it was confirmed that this lesion, in male homosexuals, in a precursor and marker of AIDS. The diagnosis of HL warrant all efforts to protect the immune system and avoid progression to AIDS.

Therapeutic evaluation of the oral retinoid Ro 10-9359 in several non-psoriatic dermatoses.

Forty-five patients suffering from various genodermatoses and erythematous, scaling, non-psoriatic dermatoses were treated orally with the aromatic derivative of retinoic acid, Ro 10-9359 (Tigason). In the genodermatoses the best results were obtained in ichthyosis, keratodermias and Darier's disease (95.6% good to excellent).