Publications by authors named "P Vias"
Synchronous primary tumors amd distant metastasis detected on F-FDG PET in patients with head and neck carcinoma.
Asia Ocean J Nucl Med Biol
January 2025
Article Synopsis
- The study focuses on the effectiveness of F-FDG PET/CT in identifying distant metastasis and synchronous tumors in newly diagnosed head and neck cancer patients in North India.
- A total of 281 patients were analyzed, revealing that 11.7% had distant metastases, primarily found in the lungs and bones, while 7% had synchronous malignancies, with lung cancer being the most common.
- These results support the use of whole body F-FDG PET/CT for initial staging as it significantly impacts patient management by detecting additional malignancies early on.
Adjuvant Radiotherapy in Bladder Cancers: A Dosimetric Study Focusing on Ileal Conduit Sparing.
Clin Oncol (R Coll Radiol)
October 2024
Purpose: To compare ileal conduit (IC) and other organ at risk (OAR) dosimetry between treatment techniques in a prospective cohort of patients planned for adjuvant radiotherapy (RT) after radical cystectomy and IC reconstruction.
Methods And Materials: Computed tomography (CT datasets of twenty patients who underwent adjuvant RT were obtained and used prospectively for delineation of target volumes (primary and nodal) and OARs, including IC, uretero-ileal anastomosis and ileal stoma using a specified protocol for simulation including a delayed CT to identify IC. Three RT plans were generated for each patient for a dose of 54 gray (Gy) in 27 fractions (PTV V95% >95%): 3-dimensional conformal radiotherapy (3DCRT) with (3DCRT_S) and without (3DCRT_N) stoma shielding, and volumetric modulated arc therapy (VMAT), with OAR constraints specified for VMAT plans (IC: Dmax<54Gy, V50Gy < 20 cc).
Purpose: We undertook a prospective planning study to describe the delineation of ileal conduit (IC) loop on radiotherapy planning computed tomography (RTP CT) scan as an organ at risk (OAR) and its sparing using volumetric modulated arc therapy (VMAT) during adjuvant irradiation of bladder malignancies.
Materials And Methods: Fifteen patients with bladder malignancy needing adjuvant radiotherapy postoperatively and having normal renal function underwent delayed phase RTP CT from June 2020 to March 2021, with certain modifications (Foley's catheter through stoma, additional delayed scans). We identified the course of ureters, external stoma, IC, and uretero-ileal (right and left) anastomotic sites.
Background: Leiomyosarcomas of urinary bladder constitute rare malignant sarcomas with very few cases reported in literature.
Case Presentation: Here, we present a case of bladder leiomyosarcoma in a well-preserved female. She failed to respond to standard chemotherapy and had a rapidly downhill course with unusual metastases in anastomotic site and peritoneum soon after surgery.