Publications by authors named "P Verhoef"
Article Synopsis
- This study focuses on identifying different immune profiles in sepsis patients based on their body temperature patterns to potentially enable more targeted treatments.
- Researchers categorized 3,576 hospitalized patients with suspected infections into four distinct temperature trajectory subphenotypes and assessed their clinical outcomes and biomarker levels.
- Findings revealed significant differences in mortality rates among these subphenotypes, with the highest mortality in hypothermic patients and notable differences in 20 specific biomarkers across the temperature groups, highlighting the complexity of sepsis.
Article Synopsis
- Combined internal medicine-pediatrics (med-peds) residency offers a unique training pathway, accredited since 1967, with over 10,000 graduates.
- Med-peds graduates can enter combined fellowships, reducing training time by one year compared to separate fellowships.
- The review discusses the benefits and challenges of pursuing combined fellowship training in fields like pulmonary and critical care medicine, along with steps for board certification.
Importance: The people of Hawai'i have both high rates of health insurance and high levels of racial and ethnic diversity, but the degree to which insurance status and race and ethnicity contribute to health outcomes in COVID-19 remains unknown.
Objective: To evaluate the associations of insurance coverage, race and ethnicity (using disaggregated race and ethnicity data), and vaccination with outcomes for COVID-19 hospitalization.
Design, Setting, And Participants: This retrospective cohort study included hospitalized patients at a tertiary care medical center between March 2020 and March 2022.
Background: Trajectories of bedside vital signs have been used to identify sepsis subphenotypes with distinct outcomes and treatment responses. The objective of this study was to validate the vitals trajectory model in a multicenter cohort of patients hospitalized with COVID-19 and to evaluate the clinical characteristics and outcomes of the resulting subphenotypes.
Research Question: Can the trajectory of routine bedside vital signs identify COVID-19 subphenotypes with distinct clinical characteristics and outcomes?
Study Design And Methods: The study included adult patients admitted with COVID-19 to four academic hospitals in the Emory Healthcare system between March 1, 2020, and May 31, 2022.