Publications by authors named "P Velmurugan"
Paediatric medulloblastomas with chromothripsis are characterised by high genomic instability and are among the tumours with the worst prognosis. However, the molecular makeup and the determinants of the aggressiveness of chromothriptic medulloblastoma are not well understood. Here, we apply spatial transcriptomics to profile a cohort of 13 chromothriptic and non-chromothriptic medulloblastomas from the same molecular subgroup.
View Article and Find Full Text PDFIntroduction: Osseous hemorrhage following a surgical incision or traumatic fracture can be a challenging issue to manage. During orthopedic surgeries, bone wax is frequently utilized as a surgical technique to enhance hemostasis and reduce bleeding from bone. The hemostatic effect of bone wax mostly stems from its physical characteristics.
View Article and Find Full Text PDFArticle Synopsis
- The study highlights the environmental and economic threats posed by the overabundance of Prosopis juliflora (PJ) fibers in developing countries and proposes using these fibers in polymer composites as a solution.
- The focus is on creating a composite material by mixing PJ fibers with a polylactic matrix and zinc oxide nanofillers, utilizing the hand layup technique for fabrication.
- Results indicate that the zinc oxide filler significantly improves the mechanical properties (like tensile and flexural strength) and thermal behavior (like thermal conductivity and heat resistance) of the PJ composite, with specific strength values reported for sample S5.
Alternative to synthetic dyes containing harmful compounds, dyes derived from natural sources are gaining popularity due to their safer and eco-friendly nature. This study focuses on extracting red dye from Basella alba fruit and optimising the extraction methods, including ultrasonic bath, ultrasonic probe, and direct heating. The extracted dye was then used for dyeing cotton, silk, and leather without needing a mordant.
View Article and Find Full Text PDFIntroduction: Infections caused by are a major cause of health concerns in the hospital setting. Moreover, the presence of extreme drug resistance in has made the scenario more challenging due to limited treatment options thereby encouraging the researchers to explore the existing antimicrobial agents to combat the infections caused by them. This study focuses on the susceptibility of multi-drug-resistant (MDR-AB) strains to minocycline and also to colistin.
View Article and Find Full Text PDF