Publications by authors named "P Van Den Winkel"
Article Synopsis
- Large-scale superconducting quantum processors face challenges due to the complex microscopic features in solid-state devices, primarily using aluminium oxide (AlO) tunnel Josephson junctions for nonlinearity in quantum operations.
- Traditional analyses often rely on an ideal sinusoidal current-phase relation, which only applies in very low-transparency conditions, but new findings reveal this doesn’t accurately represent the energy spectra of transmon artificial atoms.
- A mesoscopic model shows significant contributions from higher Josephson harmonics, improving predictions of energy spectra and suggesting that engineered harmonics could minimize charge-related errors in transmon qubits, enhancing their performance for quantum technologies.
The design of quantum hardware that reduces and mitigates errors is essential for practical quantum error correction (QEC) and useful quantum computation. To this end, we introduce the circuit-Quantum Electrodynamics (QED) dual-rail qubit in which our physical qubit is encoded in the single-photon subspace, [Formula: see text], of two superconducting microwave cavities. The dominant photon loss errors can be detected and converted into erasure errors, which are in general much easier to correct.
View Article and Find Full Text PDFMesoscopic Josephson junctions, consisting of overlapping superconducting electrodes separated by a nanometre-thin oxide layer, provide a precious source of nonlinearity for superconducting quantum circuits. Here we show that in a fluxonium qubit, the role of the Josephson junction can also be played by a lithographically defined, self-structured granular aluminium nanojunction: a superconductor-insulator-superconductor Josephson junction obtained in a single-layer, zero-angle evaporation. The measured spectrum of the resulting qubit, which we nickname gralmonium, is indistinguishable from that of a standard fluxonium.
View Article and Find Full Text PDFBackground: Monocyte-derived macrophages or dendritic cells are of increasing interest for cellular therapeutic products to treat inflammation-related diseases and cancer. However, the isolation method and the culture conditions applied influence the functionality of cells. For some approaches, the adhesion-induced differentiation into macrophages must be prevented to maintain functions attributed to circulating monocytes.
View Article and Find Full Text PDFBackground: To explore the effectiveness and safety of the gonadotropin-releasing hormone antagonist, Degarelix, for the treatment of advanced hormone-dependent prostate cancer (PCa) in a real-world setting.
Methods: In this noninterventional study, patients with advanced hormone-dependent PCa were included. Primary endpoints were progression-free survival (PFS) failure defined as either prostate-specific antigen failure, additional therapy related to PCa, or death.