Publications by authors named "P Vallerio"
Article Synopsis
- The study addresses the growing concern of cardiovascular diseases (CVDs) among adolescent and young adult (AYA) survivors of breast cancer due to the cardiotoxic effects of cancer treatments.
- Researchers developed a Bayesian network model using data from over a thousand young female BC survivors to predict CVD risk, achieving strong classification performance and clear causal relationships.
- An application was created to provide individual risk assessments for patients, aimed at helping clinicians personalize follow-up care for AYA BC survivors at higher risk of developing CVDs.
Background: Septic shock is a severe form of sepsis marked by hypotension with an ominous outcome despite the introduction of modern intensive care. The aim of the present study is to obtain a panel with biomarkers, echocardiographic and vascular parameters to better risk stratify patients and identify those at higher risk of ominous outcome.
Methods: Between May 2013 and April 2016, 35 consecutive patients admitted at the Intensive Care Unit (ICU) of ASST Great Metropolitan Hospital Niguarda with the diagnosis of severe sepsis or septic shock were enrolled.
Background: Vascular endothelial growth factor receptor (VEGFR)-targeted tyrosine kinase inhibitors (TKIs) are widely used in cancer treatment and burdened by cardiovascular toxicity. The majority of data come from clinical trials, thus in selected populations. The aim of our study is to evaluate the cardiotoxicity profile of VEGFR-targeted TKIs and the impact of cardiovascular risk factors in a real-life population.
View Article and Find Full Text PDFBackground And Aims: Uric Acid (UA) has been related to the development of Cardio-Vascular (CV) events in patients affected by Chronic Coronary Syndromes (CCS). Among various hypothesis, two arise: UA may negatively act on coronary artery determining a higher degree of atherosclerotic disease, and/or on heart determining a higher prevalence of diastolic dysfunction. Both the above hypothesized effects are object of our investigation.
View Article and Find Full Text PDFArticle Synopsis
- Atherosclerosis leads to reduced blood flow, affecting organ performance and contributing to cognitive decline in the elderly, particularly during stress.
- The study evaluated 189 hospitalized patients aged 65 and older to see if the ankle-brachial index (ABI) could predict their in-hospital functional status and complications.
- Findings showed a significant correlation between ABI and functional abilities in daily activities, suggesting that lower ABI is linked to greater functional impairment in elderly patients during hospitalization.