The effect of portocaval shunt on hepatic glycogen stores during fasting.

The effect of a prolonged fast was studied in surgically portocaval shunted (PCS) rats. This shunt excludes the liver from the direct effect of pancreatic and enteric hormones, thus facilitating the study of the biochemical and metabolic effects of these hormones. In portocaval shunted rats, liver glycogen was lower than that of control rats, and remained unaffected during fasting.

Liver revascularization with the left gastric artery following portocaval shunt in rats: technique and preliminary results.

The technique of liver arterialization with the left gastric artery after portocaval shunt in the rat is described. The operation was carried out with three different modalities, and the best results were obtained when suturing was carried out after enlargement of the arterial caliber (0.4-0.

Effects of ACTH on adrenocortical cells autotransplanted in the rat spleen: ultrastructural and morphometric observations.

The effects of chronic ACTH administration on adrenocortical cells autotransplanted in the rat spleen have been investigated. Morphometry showed that ACTH induced a significant hypertrophy of adrenocortical cells, which was mainly due to the increase in the smooth endoplasmic reticulum and mitochondrial compartment. Competitive protein binding assay demonstrated that adrenocortical cell hypertrophy was associated with a two-fold rise in the plasma corticosterone concentration.