Association of IL1RN VNTR and NKG2A polymorphisms with hepatitis E infection, a case study from western India.

Interleukin 1 receptor antagonist (IL1RN) is a competitive inhibitor of interleukin 1 (IL-1). Natural killer cells (NK cells) contribute to the elimination of viruses by their antiviral effector function, which depends on a balance between inhibitory and activating receptor genes such as NKG2D and NKG2A. Using polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) assays, the association of intronic single-nucleotide polymorphisms (SNPs) in these genes with viral infection were assessed in 111 patients with hepatitis E virus (HEV) infection and 222 HEV-naive healthy controls.

Navigating Drug-Induced Lung Disease (DILD): A Comprehensive Review on Management and Prevention Strategies.

Drug-induced lung disease (DILD) is a significant and often overlooked adverse effect of pharmacological treatments, encompassing a range of pulmonary disorders triggered by medications. This review provides a comprehensive overview of DILD, focusing on its definition, pathophysiology, and clinical implications. We explore the epidemiology of DILD, highlighting the prevalence of various drugs associated with pulmonary toxicity and the factors influencing susceptibility.

Atypical Presentations of Myasthenia Gravis as Acute Respiratory Failure: A Rare Case.

Myasthenia gravis (MG) is a chronic neuromuscular disease characterized by the progressive weakness of voluntary muscles, which encompass those in the face, throat, diaphragm, and those attached to bones. Patients commonly present with specific muscle weakness, such as difficulty in eye movement, facial expression, or swallowing, rather than generalized fatigue. However, as the disease advances, the majority of patients develop respiratory symptoms, which can significantly impact their quality of life.