The authors studied the linear blood flow rate (LBFR) in the middle cerebral artery (MCA) which was measured by means of transcranial dopplerography during carotid endarterectomy in 25 patients. Analysis of the results showed that the changes of LBFR in the MCA correlate with alterations in blood pressure: LBFR in the MCA reduced most during compression of the common carotid artery in patients with considerable affection of the contralateral carotid artery. The maximal increase of the blood flow during compression of the common carotid artery occurred when the initial LBFR in the MCA was lowest.
View Article and Find Full Text PDFThe antinociceptive effect of dalargin was studied by its influence on the amplitude of somatosensory induced potentials (IP) and by changes in the threshold pain sensitivity to heat stimulation. It was shown that it was necessary to taken into account the patients' individual sensitivity to the drug. The influence of dalargin on IP in the pre-operative period was compared with the quality of its analgetic defence in surgical interventions.
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