[Surgical treatment of perianal abscess and fistula-in-ano in neonates and infants].

Objective: To compare the incision and drainage of perianal abscess (ID) without fistulotomy with Gabriel procedure (GP) in neonates and infants with perianal abscess and fistula-in-ano.

Material And Methods: A single-center retrospective comparative study included neonates and infants aged 1-12 months with first occuring perianal abscess and fistula-in-ano. Postoperative follow-up was 1 year.

Resuscitation-promoting factors (Rpf): in search of inhibitors.

Resuscitation promoting factors (Rpf) are a family of proteins secreted by actively growing actinobacteria, including Mycobacterium tuberculosis. Experimental evidence suggests that Rpfs play a distinct role in bacterial resuscitation and re-growth as well as reactivation of chronic tuberculosis in mice. The striking similarity of the Rpfs structure to cell wall hydrolysing enzymes has provided a basis for the development of novel low molecular weight inhibitors of Rpfs activity.