[OCCUPATIONAL CANCER RISK. ASPECTS. EXPERTISES].

This paper describes the problems associated with the solution of the expert questions with regard to the occupation-related malignant tumors. There are proposed approaches for the constructing a system of the reasoned expert decisions based on the results provided by the International Agency for Research of Cancer and the retrospective assessment of individual cancer risk.

[Using the evaluation of carcinogenic risk in the mining and metallurgical enterprises of the Arctic].

The aim of this study--hygienic assessment of the contribution of factors of working environment) in the formation of carcinogenic risk to the mining and metallurgical enterprises of the Far North, the establishment of the structural features of cancer pathology among workers of these enterprises, quantitative evaluation of individual professional cancer risk in different nosological forms and morphological variants of malignant neoplasms.

[Clinical and diagnostic value of heart rate variabilities in workers exposed to noise and vibration].

Noise and vibration cause disorders of vegetative regulation of cardiovascular system. Daily ECG monitoring with heart rate variabilities analysis enables quanitative evaluation of disordered vegetative control over heart rate and diagnosis of cardioneuropathy caused by long occupational exposure to noise and vibration.

[Industrial aerosols are a risk factor of oncologic diseases in underground miners].

The paper contains new data on the carcinogenicity of industrial aerosol to miners engaged to underground extraction of sulphide copper and nickel ores. Earlier appearance of oncologic diseases (lung and stomach cancer) is typical of this category of workers, exposed to higher aerogenic concentration of nickel in mine atmosphere. This fact demonstrates that the leading role in the ethiology of these diseases is played by multicomponent industrial aerosol containing nickel in the form of complex sulphides.

[On carcinogenic effects of sulfate copper and nickel ore].

Underground mines are places for extraction of three types of copper and nickel sulfide ores: rich, copper and incorporated--those three ones differ in mimeralogic and chemical contents. Experimental evaluation of carcinogenic effects obtained during intratracheal administration of copper and incorporated ores indicates the certain carcinogenic activity of the dust with 0.49-1.