Dr. Parimal Samir works in the field of host-pathogen interactions. In this mSphere of Influence article, he reflects on how the manuscript entitled " gene synthesis by an antiviral reverse transcriptase" by Samuel Sternberg and colleagues made an impact by reminding him that there is still so much to discover in life sciences.
View Article and Find Full Text PDFAim: The aim of this study was to perform a comparative evaluation of the length of resin tags produced by three different types of pit and fissure sealants (Embrace WetBond, Helioseal Clear, and Fuji VII) using scanning electron microscopy.
Materials And Methods: Thirty extracted mandibular premolars were randomly divided into three groups of ten. Each group was treated with one of the sealants - Embrace WetBond, Helioseal Clear, or Fuji VII.
Viral variant is one known risk factor associated with post-acute sequelae of COVID-19 (PASC), yet the pathogenesis is largely unknown. Here, we studied SARS-CoV-2 Delta variant-induced PASC in K18-hACE2 mice. The virus replicated productively, induced robust inflammatory responses in lung and brain tissues, and caused weight loss and mortality during the acute infection.
View Article and Find Full Text PDFAim: To determine postoperative pain after root canal instrumentation using manual K-file and rotary Kedo-S files in primary molars.
Material And Method: Thirty-six primary mandibular molars from 4- to 8-year-old children requiring pulpectomy were randomly split into two groups of 18 teeth each, that is, manual file K-file (Group I) and Kedo-S rotary file (Group II). Children's pre- and postoperative pain was assessed using a four-point scale at different time intervals.